Latest news articles

Added 21 days ago Drug news

CHMP recommends approval of Isturisa for use in Cushing's Syndrome.- Recordati

Recordati has announced that the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting...

Added 25 days ago Drug news

Complete Response Letter from FDA to Lipocine Inc., for Tlando for testosterone replacement therapy.

Lipocine Inc. announced that it has received a Complete Response Letter from the FDA regarding its New Drug Application ("NDA")...

Added 1 month ago Drug news

Positive phase III top-line results for Somatrogon, an investigational long-acting human growth hormone to treat children with growth hormone deficiency.- Opko Health + Pfizer

OPKO Health Inc and Pfizer Inc. announced that the global Phase III trial evaluating somatrogon dosed once-weekly in pre-pubertal children...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cushing's Syndrome

Cushing's Syndrome

Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?

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Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

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Guidelines

Hyperparathyroidism (primary): diagnosis, assessment and initial management

This guideline covers diagnosing, assessing and managing primary hyperparathyroidism. It aims to improve recognition and treatment of this condition, reducing long‑term complications and improving quality of life.

Added 3 months ago

Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition

Chronic diarrhoea is a common problem, hence clear guidance on investigations is required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea...

Added 1 year ago

Guidelines on Male Hypogonadism

Androgens play a crucial role in the development and maintenance of male reproductive and sexual functions. Low levels of circulating androgens can cause disturbances in male sexual development, resulting in congenital abnormalities...

Added 4 years ago

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Journal articles

Treatment challenges in pediatric Cushing's disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence.

Cushing’s disease (CD) is a rare endocrine condition caused by a corticotroph pituitary tumor that produces adrenocorticotropic hormone. The current state of knowledge of CD treatment is presented in this article including factors...

Added 11 days ago

Long-term efficacy and safety of once-monthly pasireotide in Cushing's disease: A Phase III extension study.

Objectives: Many patients with Cushing's disease (CD) require chronic pharmacotherapy to control their hypercortisolism. We evaluated the efficacy and safety of long‐acting pasireotide during a long‐term extension study...

Added 11 days ago

Surgical and radiosurgical treatment strategies for Cushing's disease.

Introduction: Cushing’s disease (CD) is rare disorder that should be adequately managed to optimize long-term prognosis. Treatment of CD is multidisciplinary and often includes surgical resection, adjuvant stereotactic...

Added 11 days ago

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Clinical trials

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Disease

Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with Cushing's disease.

Added 5 months ago

Open-label Treatment in Cushing's Syndrome (OPTICS)

This is a long-term, OLE study of levoketoconazole in subjects with endogenous CS who have completed one or both parent studies or otherwise potentially qualify for this study, as defined in the eligibility criteria.

Added 5 months ago

Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

This phase 2 multicenter, open-label clinical trial will evaluate safety and efficacy of 4 weeks of oral seliciclib in patients with newly diagnosed, persistent, or recurrent Cushing disease.

Added 5 months ago

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Monica Caliber

I am a medical writer with a Master Degree in Nutrition from the University of Stockholm and the Karolinska Institute, Sweden, and have done PhD level coursework at Baylor University, TX. USA. I specialize in preventive medicine and testosterone deficiency/treatment. Having lost my father ... Read more

Hypogonadism – why important to diagnose and treat?

Most clinicians and patients think that the purpose of treating hypogonadism is to merely relieve symptoms. However, this only scratches the surface... 

CME

Step by step: how to diagnose and manage type 1 diabetes in adults in primary care

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BMJ Learning - British Medical Learning
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Diabetic ketoacidosis in adults

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BMJ Learning - British Medical Learning
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Clinical pointers: recognising and managing acute complications of diabetes in adults

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BMJ Learning - British Medical Learning
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Search all CME for Other endocrine disorders