Latest news articles

Added 4 days ago Drug news

Phase III fliGHt trial shows TransCon Growth Hormone safe in pediatric growth hormone deficiency

Ascendis Pharma announced preliminary results from the phase III fliGHt Trial of TransCon Growth Hormone (hGH). The results indicated treatment...

Search all news articles for Other endocrine disorders
 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cushing's Syndrome

Cushing's Syndrome

Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?

+ 2 more

Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

Load more

Guidelines

Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition

Chronic diarrhoea is a common problem, hence clear guidance on investigations is required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea...

Added 11 months ago

Guidelines on Male Hypogonadism

Androgens play a crucial role in the development and maintenance of male reproductive and sexual functions. Low levels of circulating androgens can cause disturbances in male sexual development, resulting in congenital abnormalities...

Added 4 years ago

International evidence-based guideline for the assessment and management of polycystic ovary syndrome 2018

Objective: To develop and translate rigorous, comprehensive evidence-based diagnosis, assessment and treatment guidelines, to improve the lives of women with polycystic ovary syndrome (PCOS) worldwide.

Added 9 months ago

Search all guidelines for Other endocrine disorders
 

Journal articles

The diagnostic accuracy of increased late night salivary cortisol for Cushing's syndrome: a real-life prospective study.

Introduction and aim: A prompt diagnosis of Cushing’s Syndrome (CS) in high-risk populations is mandatory: 1-mg dexamethasone suppression test (1-mg DST), late night salivary cortisol (LNSC), and urinary-free cortisol (UFC)...

Added 1 month ago

Diagnostic value of the late-night salivary cortisol in the diagnosis of clinical and subclinical Cushing's syndrome: results of a single-center 7-year experience.

Late-night salivary cortisol (LNSaC) is an easy-to-use test reflecting the free cortisol level in the serum and does not require hospitalization. Controlled studies reported that LNSaC has a high sensitivity and specificity...

Added 1 month ago

Alterations in Protein Kinase A Substrate Specificity as a Potential Cause of Cushing Syndrome.

Cushing syndrome is a severe endocrine disorder of cortisol excess associated with major metabolic and cardiovascular sequelae. We recently identified somatic mutations in PRKACA, the gene encoding the catalytic (C) α subunit...

Added 1 month ago

Search all journal articles for Other endocrine disorders
 

Clinical trials

A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome (GRACE)

This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the safety and efficacy of relacorilant in patients with endogenous Cushing syndrome and concurrent 1) Type 2 diabetes mellitus/impaired...

Added 2 months ago

A Study to Assess the Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing's Syndrome.

This is a double-blind, randomized, placebo-controlled withdrawal and rescue/restoration study in subjects with endogenous CS previously treated with single-arm, open-label levoketoconazole that will assess efficacy, safety, tolerability, and...

Added 2 months ago

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

The purpose of the study is to evaluate the effect of telotristat etiprate versus placebo on the incidence of treatment-emergent adverse events and on 5-hydroxyindoleacetic acid (5-HIAA) levels.

Added 6 years ago

Search all clinical trials for Other endocrine disorders
 
Monica Caliber

I am a medical writer with a Master Degree in Nutrition from the University of Stockholm and the Karolinska Institute, Sweden, and have done PhD level coursework at Baylor University, TX. USA. I specialize in preventive medicine and testosterone deficiency/treatment. Having lost my father ... Read more

Hypogonadism – why important to diagnose and treat?

Most clinicians and patients think that the purpose of treating hypogonadism is to merely relieve symptoms. However, this only scratches the surface... 

CME

Step by step: how to diagnose and manage type 1 diabetes in adults in primary care

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Diabetic ketoacidosis in adults

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Clinical pointers: recognising and managing acute complications of diabetes in adults

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
Search all CME for Other endocrine disorders