Latest news articles

Added 30 days ago Drug news

Positive results from phase III BLISS-LN trial of Benlysta to treat lupus nephritis.- GSK

GSK announced positive headline results for intravenous (IV) Benlysta (belimumab) in the largest controlled phase III study in active lupus...

Added 1 month ago Drug news

AURORA phase III trial of Luveniq meets primary endpoint in lupus nephritis.- Aurinia Pharma

Aurinia Pharmaceuticals Inc. announced positive top-line results announced positive efficacy and safety results from its pivotal AURORA Phase III trial...

Added 1 year ago Drug news

Recordati to market Cystagon in Europe for nephropathic cystinosis.- Mylan

Recordati announces the completion of an agreement with Mylan for the acquisition of the rights to Cystagon (cysteamine bitartrate), indicated...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

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Guidelines

KDIGO Clinical Practice Guideline for Glomerulonephritis

The 2011 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Glomerulonephritis (GN) aims to assist practitioners caring for adults and children with GN.

Added 7 years ago

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Journal articles

Potential nephrotoxicity of sofosbuvir-based treatment in patients infected with hepatitis C virus: a review on incidence, type and risk factors.

Introduction: There was no report of nephrotoxicity during clinical trials assessed sofosbuvir for treatment of hepatitis C (HCV) infection. This may be due to excluding patients with severe kidney dysfunction...

Added 1 year ago

Fcγ Receptor IIIa Single–Nucleotide Polymorphisms and Haplotypes Affect Human IgG Binding and Are Associated With Lupus Nephritis in African Americans

Objective:To investigate whether the Fcγ receptor IIIa–66L/R/H (FcγRIIIa–66L/R/H) polymorphism influences net effective receptor function and to assess if the FCGR3A...

Added 5 years ago

Efficacy and Safety of Ocrelizumab in Active Proliferative Lupus Nephritis: Results From a Randomized, Double-Blind, Phase III Study

Objective:To investigate the efficacy and safety of ocrelizumab in patients with class III/IV lupus nephritis (LN).Methods:Patients were randomized 1:1:1 to...

Added 6 years ago

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