Added 30 days ago Drug news
GSK announced positive headline results for intravenous (IV) Benlysta (belimumab) in the largest controlled phase III study in active lupus...
Added 1 month ago Drug news
Aurinia Pharmaceuticals Inc. announced positive top-line results announced positive efficacy and safety results from its pivotal AURORA Phase III trial...
Added 1 year ago Drug news
Recordati announces the completion of an agreement with Mylan for the acquisition of the rights to Cystagon (cysteamine bitartrate), indicated...
An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.
Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.
See information on best practice in solid organ transplantation, and expert discussions on related hot topics.
The Atopic Dermatitis Knowledge Centre is an educational resource, intended for healthcare professionals, that provides credible medical information on the epidemiology, pathophysiology and burden of atopic dermatitis, as well as diagnostic techniques, treatment regimens and guideline recommendations.
Anticoagulation therapy for Stroke Prevention Learning Zone offers a deep-dive into atrial fibrillation causes, consequences, diagnosis and management to help you deliver optimal care and prevent strokes in patients living with this common arrhythmia.
The 2011 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Glomerulonephritis (GN) aims to assist practitioners caring for adults and children with GN.
Added 7 years ago
Potential nephrotoxicity of sofosbuvir-based treatment in patients infected with hepatitis C virus: a review on incidence, type and risk factors.
Introduction: There was no report of nephrotoxicity during clinical trials assessed sofosbuvir for treatment of hepatitis C (HCV) infection. This may be due to excluding patients with severe kidney dysfunction...
Added 1 year ago
Fcγ Receptor IIIa Single–Nucleotide Polymorphisms and Haplotypes Affect Human IgG Binding and Are Associated With Lupus Nephritis in African Americans
Objective:To investigate whether the Fcγ receptor IIIa–66L/R/H (FcγRIIIa–66L/R/H) polymorphism influences net effective receptor function and to assess if the FCGR3A...
Added 5 years ago
Efficacy and Safety of Ocrelizumab in Active Proliferative Lupus Nephritis: Results From a Randomized, Double-Blind, Phase III Study
Objective:To investigate the efficacy and safety of ocrelizumab in patients with class III/IV lupus nephritis (LN).Methods:Patients were randomized 1:1:1 to...
Added 6 years ago