Latest news articles

Added 7 days ago Drug news

Phase III MOUNTAIN Study of SAGE 217 fails to meet endpoint in major depressive disorder.- Sage Therapeutics

Sage Therapeutics reported topline results from the pivotal Phase III MOUNTAIN Study evaluating the effect of SAGE 217 (zuranolone) on...

Added 1 month ago Drug news

CHMP recommends Spravato nasal spray for adults with treatment-resistant major depressive disorder.- Janssen Cilag

The Janssen Pharmaceutical Companies of Johnson & Johnson announced that the Committee for Medicinal Products for Human Use (CHMP) of...

Added 3 months ago Drug news

Phase III clinical studies of Spravato meet endpoints in depression

The Janssen Pharmaceutical Companies of Johnson & Johnson announced positive results from two pivotal Phase III clinical studies (ASPIRE I...

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Learning Zones

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Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Depression in children and young people: identification and management

This guideline covers the identification and treatment of depression in children (5–11 years) and young people (12–18 years) in primary, community and secondary care.

Added 14 years ago

Antenatal and postnatal mental health: clinical management and service guidance

This guideline covers recognising, assessing and treating mental health problems in women who are planning to have a baby, are pregnant, or have had a baby or been pregnant in the past year.

Added 5 years ago

Depression in adults: recognition and management

This guideline covers identifying and managing depression in adults aged 18 years and older, in primary and secondary care.

Added 10 years ago

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Journal articles

Treatment for depression comorbid with dementia.

Depression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an increase in...

Added 2 months ago

Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy.

Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover, the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities. The neurobehavioral comorbidities discussed...

Added 6 months ago

The Roles of Apathy and Depression in Predicting Alzheimer Disease: A Longitudinal Analysis in Older Adults With Mild Cognitive Impairment.

Objective: Apathy and depression have each been associated with an increased risk of conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD).These symptoms often co-occur and the contribution...

Added 6 months ago

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Clinical trials

A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder

This study will evaluate the safety and tolerability of brexpiprazole (OPC-34712) in the treatment of subjects with bipolar I disorder. All subjects will receive a starting dose of brexpiprazole which will be titrated up in subsequent visits.

Added 2 years ago

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01)

This study will evaluate the efficacy, safety, and tolerability of rapastinel 450 mg compared to placebo adjunctive to antidepressant therapy (ADT) in patients with major depressive disorder (MDD) who have a partial response to ADT.

Added 2 years ago

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Evaluating the efficacy of vortioxetine 10 mg/day and 20 mg/day versus placebo on depressive symptoms in adolescents (age ≥12 and ≤17 years) with a DSM-5™ [...] diagnosis of Major depressive disorder (MDD).

Added 2 years ago

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Bob Bury

I’m a retired radiologist, and I keep myself busy with hill-walking, fishing and medical journalism/blogging, but mostly I’m a provider of free healthcare for my grandchildren. I am also accredited by the British Humanist Association to officiate at non-religious funerals: http... Read more

Community Mental Health Provision then and now - is all progress positive?

Bob Bury muses on the state of modern mental healthcare. Instead of asylums, patients are now part of the community. But what of those who fall through the cracks? How can GPs help patients who need emergency mental health care? Can we learn anything from the methods of the past? Are three letter acronyms helpful? Examining the politics and hurdles of the UK's modern Community Mental Health provision, Bob Bury questions what UK healthcare professionals can do better and how things should change.

CME

Assessing anxiety in palliative care patients

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
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Management of depression

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MIMS Learning - Monthly Index of Medical Specialities
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Depression in adults with a chronic health problem: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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1
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1
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90
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