Latest news articles

Added 1 day ago Drug news

Interim data from BRIDGE Phase III study of PRX 102 shows efficacy in Fabry disease.- Protalix BioTherapeutics

Protalix BioTherapeutics announced positive 12-month on-treatment data from the first 16 out of the 22 adult patients with Fabry disease...

Added 8 days ago Drug news

FDA approves Scenesse for the rare dermatology disorder of erythropoietic protoporphyria. - Clinuvel Pharmaceuticals

Clinuvel Pharmaceuticals Ltd. has worked for more than a decade to bring Scenesse (afamelanotide) to the US market for the...

Added 18 days ago Drug news

FDA approves label extension for Crysvita in X-linked hypophosphatemia.- Ultragenyx Pharmaceutical/Kyowa Kirin

Ultragenyx Pharmaceutical and Kyowa Kirin announced that the FDA has approved a label expansion for Crysvita (burosumab) in X-linked hypophosphatemia....

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

Sleep Apnea

Sleep Apnea

Sleep apnea is a chronic condition characterised by recurrent interruptions in breathing throughout the sleep cycle. Learn about the two main types of sleep apnea and hear from experts as they present the latest research at the Sleep and Breathing conference (Marseille, 2019).

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Guidelines

UK Commissioning guide: Massive Weight Loss Body Contouring

This document is about guidance for commissioning reconstructive procedures, post massive weight loss and is based on the best available evidence.

Added 1 year ago

Emergency management of acute hypercalcaemia in adult patients

Abnormalities of parathyroid function, bone resorption, renal calcium reabsorption or dihydroxylation of vitamin D may cause regulatory mechanisms to fail and serum calcium may rise.

Added 6 years ago

Acute Hypocalcaemia - for use in adult patients

Acute hypocalcaemia can be life threatening, necessitating urgent treatment. In severe cases, intravenous calcium forms the mainstay of initial therapy, but it is essential to ascertain the underlying cause and commence specific therapy...

Added 6 years ago

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Journal articles

The Effects of Obesity in Asthma.

Purpose of Review: Rising costs and increasing morbidity makes the identification and treatment of high-risk asthma phenotypes important. In this review, we outline the complex relationship between obesity and asthma.

Added 2 days ago

The relationship of obesity and obstructive sleep apnea.

Obstructive sleep apnea is a common disorder, and obesity is a known risk factor for its development. The prevalence of obesity is increasing worldwide, and a corresponding increase in the prevalence of obstructive sleep apnea...

Added 3 months ago

Human plasma fibrinogen is synthesized in the liver.

Hereditary systemic amyloidosis caused by fibrinogen Aalpha-chain gene mutations is an autosomal dominant condition with variable penetrance, usually of late onset, and typically presents with nephropathy leading to renal failure.

Added 4 months ago

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Clinical trials

Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria (PKU)

This study will evaluate SYNB1618 (investigational product) in healthy volunteers (HV) and subjects diagnosed with phenylketonuria (PKU) for the possible treatment of PKU. Phenylketonuria (PKU) is a rare inherited metabolic...

Added 5 months ago

CARAT: Canagliflozin vs. placebo for post bariatric patients with persistent type 2 diabetes

This is a prospective, randomized clinical trial for patients with recurrent type 2 diabetes post-gastric bypass surgery that will compare a 6 month course of canagliflozin monotherapy vs. placebo on clinical outcomes of type 2 diabetes.

Added 3 years ago

Setmelanotide for the treatment of early-onset POMC deficiency obesity

The purpose of the study is to determine the effect of setmelanotide (RM-493) on weight and other factors in patients with pro-opiomelanocortin (POMC) deficiency obesity due to rare bi-allelic loss-of function POMC or PCSK1 genetic mutations.

Added 3 years ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.

CME

Obesity: clinical review

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The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test

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BMJ Learning - British Medical Learning
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Obesity: a guide to prevention and management - putting NICE guidelines into practice

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BMJ Learning - British Medical Learning
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90
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