Intracranial injury

Intracranial (head) injuries are a common reason for presentation to emergency services. Globally, the scale is hard to quantify, with some estimations suggesting 42 million


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Latest news articles

Added 1 year ago Drug news

FDA grants 510(k) approval for Signa Premier MRI system. GE HealthCare

GE Healthcare announces 510(k) clearance for its Signa Premier MRI system ,a new wide bore 3.0T magnetic resonance imaging (MRI)...

Added 5 years ago Drug news

FDA approves Cranial Bone Void Filler repair system

Tissue Regeneration Systems has received 510(K) approval from the FDA for its Cranial Bone Void Filler product, indicated for use...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

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Head injury: Triage, assessment, investigation and early management of head injury in children, young people and adults

This guideline covers the assessment and early management of head injury in children, young people and adults.

Added 5 years ago

Brain injury rehabilitation in adults

This guideline provides recommendations on post-acute assessment for adults over 16 years of age with brain injuries and interventions for cognitive, communicative, emotional, behavioural and physical rehabilitation.

Added 6 years ago

Early management of patients with a head injury

This guideline makes recommendations on the early management (first 72 hours of care) of adults and children with head injury. It addresses the patient journey through: prehospital assessment; referral to hospital...

Added 9 years ago

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Journal articles

Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature.

Spreading depression (SD) is a transient wave of near-complete neuronal and glial depolarization associated with massive transmembrane ionic and water shifts. It is evolutionarily conserved in the central nervous systems of...

Added 24 days ago

Evaluation of the Use of Low-Dose 4-Factor Prothrombin Complex Concentrate in the Reversal of Direct Oral Anticoagulants in Bleeding Patients.

Objective: This study investigated the percentage of patients who achieved hemostasis with 4-factor prothrombin complex concentrate (4-factor PCC) 35 U/kg.

Added 30 days ago

The effectiveness of prehospital hypertonic saline for hypotensive trauma patients: a systematic review and meta-analysis

The optimal prehospital fluid for the treatment of hypotension is unknown. Hypertonic fluids may increase circulatory volume and mute the pro-inflammatory response of the body to injury and illness.

Added 11 months ago

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