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Added 1 month ago Drug news

FDA accepts two applications for Dificid to treat children aged six months up to 18 years with Clostridium difficile infections.- Merck Inc.

Merck Inc.,has announced the FDA has accepted for review a New Drug Application (NDA) for Dificid (fidaxomicin) for oral suspension,...

Added 9 months ago Drug news

MK 7655 + Primaxin + cilastatin filed with FDA for cUTI + cIAI.- Merck Inc

Merck Inc. announced that the FDA has accepted for review regulatory filings for Priority Review for the combination of MK...

Added 11 months ago Drug news

FDA accepts Avycaz sNDA to include the treatment of complicated urinary tract infections and complicated intra-abdominal infections in pediatric patients . Allergan.

Allergan plc announced that the FDA has accepted for review the company's supplemental New Drug Application (sNDA) for AvyCaz(ceftazidime and...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Inflammatory Bowel Disease Knowledge Centre

Inflammatory Bowel Disease Knowledge Centre

The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and unmet needs and the underlying inflammatory processes that drive IBD, considering some of the key inflammatory pathways.

Inflammatory bowel disease assessment tools

Inflammatory bowel disease assessment tools

'New IBD assessment tools at a glance' - an educational symposium sponsored by Sandoz.

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Guidelines

Surgical site infections: prevention and treatment

This guideline covers preventing and treating surgical site infections in adults, young people and children who are having a surgical procedure involving a cut through the skin.

Added 11 years ago

Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition

Chronic diarrhoea is a common problem, hence clear guidance on investigations is required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea...

Added 1 year ago

Guidance document for prevention of Clostridium difficile infection in acute healthcare settings

This updated guideline provides a current review of the literature on interventions to control CDI in adult populations in acute healthcare settings and derives specific infection control recommendations.

Added 1 year ago

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Journal articles

Faecal microbiota transplantation: a regulatory hurdle?

During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.

Added 6 months ago

Bezlotoxumab: A Review in Preventing Clostridium difficile Infection Recurrence.

Bezlotoxumab (Zinplava™) is a fully human monoclonal antibody against Clostridium difficile toxin B indicated for the prevention of C. difficile infection (CDI) recurrence in patients with a high recurrence risk.

Added 2 years ago

Bezlotoxumab for the prevention of Clostridium difficile recurrence.

Introduction: Clostridium difficile infection is a major economic and clinical burden, due to its high frequency of recurrence. Currently recommended treatments are not efficient for prevention...

Added 2 years ago

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Clinical trials

ECOSPOR III - SER-109 Versus Placebo in the Treatment of Adults With Recurrent Clostridium Difficile Infection (ECOSPORIII)

The purpose of this study is to demonstrate the superiority of SER-109 vs placebo to reduce recurrence of CDI in adults up to 8 weeks after initiation of treatment.

Added 6 months ago

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD2)

This is the first prospective, multi-center, double-blinded, randomized controlled study of a microbiota suspension derived from intestinal microbes. Patients who have had at least two recurrences of C. difficile infection (CDI) after...

Added 6 months ago

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Jonathan Macdonald

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

CME

Gastroenteritis in children, GP cancer care and pre-eclampsia risk: journals update June 2016

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