Latest news articles

Added 7 hours ago Drug news

ATLAS-2M study met its primary endpoint for cabotegravir and rilpivirine administered every eight weeks compared to four-week administration. Viiv HealthCare

ViiV Healthcare, announced positive headline results from its global phase III ATLAS-2M study of the investigational, long-acting, injectable, 2-drug regimen...

Added 12 days ago Drug news

FDA Advisory Committee’s recommendation on Descovy for pre-exposure prophylaxis

Gilead Sciences, Inc. announced that the Antimicrobial Drugs Advisory Committee (AMDAC) of the FDA recommended approval of Descovy...

Added 16 days ago Drug news

Ontario provides access to Biktarvy for the treatment of HIV

Gilead Sciences Canada, Inc. announced that effective July 31, the Ontario Drug Benefit Program will provide eligible patients with access...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

EADV 2018 Highlights

EADV 2018 Highlights

EADV Congress 2018: Bringing you the latest news and insights from 27th EADV Congress, 12-16 September 2018 Paris, France.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

British HIV Association guidelines for the management of HIV infection in pregnant women 2018

The overall purpose of these guidelines is to provide guidance on best clinical practice in the treatment and management of pregnant women living with HIV (human immunodeficiency virus) in the UK and their infants.

Added 5 years ago

EACS GUIDELINES Version 9.0 October 2017

EACS produces the European Guidelines for treatment of HIV-positive adults in Europe.

Added 1 year ago

British HIV Association guidelines for the routine investigation and monitoring of adult HIV-1-positive individuals 2016

As with the previous monitoring guideline, the aim is to present a consensus regarding the standard assessment and investigation of HIV infection from the time of diagnosis and to describe the appropriate monitoring of HIV-positive individuals...

Added 7 years ago

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Journal articles

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.

An HIV-1-infected adult underwent allo-HSCT for Hodgkin's lymphoma using cells from a CCR5Δ32/Δ32 donor. He experienced mild gut graft versus host disease.

Added 5 months ago

Darunavir for the treatment of HIV infection.

The authors present and discuss the efficacy and safety data of DRV when used in antiretroviral-naïve, multiexperienced subjects and in the setting of treatment deintensification in subjects with viral suppression.

Added 1 year ago

Switching to fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide from dolutegravir plus abacavir and lamivudine in virologically suppressed adults with HIV-1: 48 week results of a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.

Bictegravir, co-formulated with emtricitabine and tenofovir alafenamide, has shown good efficacy and tolerability, and similar bone, renal, and lipid profiles to dolutegravir, abacavir, and lamivudine, in treatment-naive adults with HIV-1...

Added 1 year ago

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Clinical trials

Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults (Alliance)

The primary objective of this study is to evaluate the efficacy of fixed-dose combination (FDC) of bictegravir/emtricitabine/ tenofovir alafenamide (B/F/TAF) versus dolutegravir (DTG) + emtricitabine/tenofovir disoproxil fumarate...

Added 1 month ago

A Study to Evaluate the Efficacy and Safety of (D/C/F/TAF) Once Daily Fixed Dose Combination (FDC) Regimen in Newly Diagnosed, Antiretroviral Treatment-naive Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Receiving Care in a Test and Treat Model of Care

The purpose of this study is to assess the efficacy of Darunavir/ Cobicistat/ Emtricitabine/ Tenofovir Alafenamide (D/C/F/TAF) fixed-dose combination (FDC) in a Test and Treat model of care in newly diagnosed human immunodeficiency virus...

Added 11 months ago

An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)

This study will compare safety, efficacy, and tolerability of a two drug regimen of dolutegravir (DTG) plus (+) lamivudine (3TC) administered once daily with DTG plus two nucleoside reverse transcriptase inhibitors...

Added 1 year ago

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Alastair Miller

I am a retired infectious disease physician with a particular interest in blood borne viruses (HIV/viral hepatitis), neurological infection and bone & joint infection. I now work part time in acute medicine and part time in medical training & education as deputy Medical Director of... Read more

What is Tropical Medicine?

At first sight this seems a question with an obvious response and not one that requires much debate in this blog. However, the answer may be more complex than it initially appears and may benefit from further exploration.