Latest news articles

Added 3 days ago Drug news

Phase III GEMINI-1 and GEMINI-2 studies of Tivicay + Epivir meet primary endpoint in HIV-1.- ViiV Healthcare.

ViiV Healthcare announced positive headline results from its phase III GEMINI-1 and GEMINI-2 studues evaluating the safety and efficacy of...

Added 27 days ago Drug news

EU approves Juluca for human immunodeficiency virus type 1.- ViiV Healthcare.

ViiV Healthcare announced that the European Commission has granted marketing authorisation for Juluca (dolutegravir 50mg/rilpivirine 25mg) for the treatment of...

Added 1 month ago Drug news

FDA expands approval of Truvada for at-risk adolescents against HIV.- Gilead Sciences.

Gilead Sciences announced that the FDA has approved once-daily oral Truvada (emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg)—in combination with...

Search all news articles for HIV infection
 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Prostate Cancer

Prostate Cancer

How can you balance the harmful effects of treatment with control of prostate cancer growth in otherwise healthy patients?

+ 5 more

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

+ 1 more

Load more

Guidelines

British HIV Association guidelines for the management of HIV infection in pregnant women 2018

The overall purpose of these guidelines is to provide guidance on best clinical practice in the treatment and management of pregnant women living with HIV (human immunodeficiency virus) in the UK and their infants.

Added 4 years ago

British HIV Association guidelines for the routine investigation and monitoring of adult HIV-1-positive individuals 2016

As with the previous monitoring guideline, the aim is to present a consensus regarding the standard assessment and investigation of HIV infection from the time of diagnosis and to describe the appropriate monitoring of HIV-positive individuals...

Added 6 years ago

British HIV Association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2015 (2016 interim update)

The overall purpose of these guidelines is to provide guidance on best clinical practice in the treatment and management of adults with HIV infection on antiretroviral therapy (ART).

Added 2 years ago

Search all guidelines for HIV infection
 

Journal articles

Efficacy, safety, and tolerability of dolutegravir-rilpivirine for the maintenance of virological suppression in adults with HIV-1: phase 3, randomised, non-inferiority SWORD-1 and SWORD-2 studies.

Background: Lifelong HIV antiretroviral therapy (ART) has prompted an interest in two-drug regimens to minimise cumulative drug exposure and toxicities. The safety, tolerability, and efficacy of dolutegravir and rilpivirine...

Added 24 days ago

Dolutegravir plus rilpivirine dual therapy in treating HIV-1 infection.

This review covers the most recent data from observational cohorts and randomized clinical trials concerning the switch to the dual combination of dolutegravir plus rilpivirine and the reasons that lead to consider this option.

Added 24 days ago

Dolutegravir-rilpivirine coformulation.

This review aims to update the current experience with the novel two-drug combination of dolutegravir (DTG) and rilpivirine (RPV) and elucidate the possible applications and limitations of coformulated DTG–RPV in the future.

Added 24 days ago

Search all journal articles for HIV infection
 

Clinical trials

Regimen Switch to Dolutegravir + Rilpivirine From Current Antiretroviral Regimen in Human Immunodeficiency Virus Type 1 Infected and Virologically Suppressed Adults (SWORD-2)

The aim of this study is to determine if virologically suppressed, human immunodeficiency virus type 1 (HIV-1) infected adults on an antiretroviral regimen (including 2 nucleoside reverse transcriptase inhibitors [NRTIs] plus a third agent)...

Added 24 days ago

Regimen Switch to Dolutegravir + Rilpivirine From Current Antiretroviral Regimen in Human Immunodeficiency Virus Type 1 Infected and Virologically Suppressed Adults (SWORD-1)

The aim of this study is to determine if virologically suppressed human immunodeficiency virus type 1 (HIV-1) infected adults on an antiretroviral regimen (including 2 nucleoside reverse transcriptase inhibitors [NRTIs] plus a third agent)...

Added 24 days ago

Study to Evaluate Efficacy of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Regimen Versus Boosted Protease Inhibitor (bPI) Along With Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) Regimen in Virologically-Suppressed, HIV-1 Infected Participants

The purpose of this study is to demonstrate non-inferiority in efficacy while switching to a once-daily single-tablet regimen containing darunavir (DRV)/ cobicistat (COBI)/ emtricitabine (FTC)/ tenofovir alafenamide (TAF) (D/C/F/TAF tablet)...

Added 4 years ago

Search all clinical trials for HIV infection
 
Alastair Miller

I am a retired infectious disease physician with a particular interest in blood borne viruses (HIV/viral hepatitis), neurological infection and bone & joint infection. I now work part time in acute medicine and part time in medical training & education as deputy Medical Director of... Read more

What is Tropical Medicine?

At first sight this seems a question with an obvious response and not one that requires much debate in this blog. However, the answer may be more complex than it initially appears and may benefit from further exploration.