Latest news articles

Added 1 month ago Drug news

Horizon Therapeutics initiates trial for Krystexxa (pegloticase injection) plus methotrexate to increase durability of response for patients living with chronic gout

Horizon Therapeutics plc announced the initiation of a clinical trial evaluating Krystexxa (pegloticase injection) in combination with methotrexate as a...

Added 2 months ago Congress news

EULAR 2019 | EXPOSURE TO INORGANIC DUST INCREASES RISK OF GOUT IN WOMEN BY 27%

Results also show that gout is more than twice as likely in alcoholic patients and more than three times as likely in obese patients.1

Added 2 months ago Congress news

EULAR 2019 | GOUT PATIENTS SUFFER IN SILENCE WITH LOW EXPECTATIONS OF TREATMENT

European survey suggests patients are satisfied with their treatment despite inadequate disease management1

Search all news articles for Gout
 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

+ 2 more

Load more

Guidelines

The British Society for Rheumatology Guideline for the Management of Gout

This guideline aims to offer revised and updated, concise, patient-focused, evidence-based, expert recommendations for the management of gout in the UK.

Added 1 year ago

2016 updated EULAR evidence-based recommendations for the management of gout

These recommendations aim to inform physicians and patients about the non-pharmacological and pharmacological treatments for gout and to provide the best strategies to achieve the predefined urate target to cure the disease.

Added 1 year ago

Search all guidelines for Gout
 

Journal articles

The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout.

The objective of the study was to evaluate the effect of lesinurad, a selective uric acid uptake inhibitor, alone and in combination with the xanthine oxidase inhibitor allopurinol, on serum uric acid and urinary urate excretion in patients with...

Added 11 months ago

Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study).

Objectives: Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised, phase III trial.

Added 11 months ago

Chronic Disease Approaches Needed to Curb Gout’s Growing Burden.

Gout’s bad rap as disease of dietary excess has sometimes obscured the complex, chronic nature of the disease and led to ineffective care for many patients.

Added 1 year ago

Search all journal articles for Gout
 

Clinical trials

Combining Lesinurad With Allopurinol in Inadequate Responders (CLEAR 1)

This study that compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who have had an inadequate response to allopurinol.

Added 8 years ago

Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat (CRYSTAL)

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with febuxostat...

Added 8 years ago

Combining Lesinurad With Allopurinol in Inadequate Responders (CLEAR 2)

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who have had an inadequate response to allopurinol.

Added 8 years ago

Search all clinical trials for Gout