Latest news articles

Added 5 days ago Drug news

Study 017 trial of safety and efficacy of YKP 3089 in focal seizures published in The Lancet Neurology.- SK Life Science

SK Life Science announced The Lancet Neurology has published results from Study 017, a multicenter, double-blind, randomized, placebo-controlled, dose-response study...

Added 7 days ago Drug news

GW Pharmaceuticals receives positive NICE recommendation for Epidyolex for the treatment of seizures in patients with two rare, severe forms of childhood-onset epilepsy.

GW Pharmaceuticals plc announces that two of its medicines, Epidyolex (cannabidiol) oral solution and Sativex (nabiximols), have been recommended by...

Added 1 month ago Drug news

European Commission approves Epidyolix for use as adjunctive therapy of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome.- GW Pharma

GW Pharmaceuticals plc , world leader in discovering, developing and commercialising cannabinoid prescription medicines, announces that the European Commission (EC)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

EPNS 2019 Congress Highlights

EPNS 2019 Congress Highlights

The epgonline.org team is creating daily reports from the 13th European Paediatric Neurology Society (EPNS) Congress, held in Athens, Greece from 17th to 21st September 2019, to bring you coverage of cutting-edge science and advances in clinical care across all fields of paediatric neurology. 

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Guidelines

Epilepsies: diagnosis and management

The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.

Added 7 years ago

Suspected neurological conditions: recognition and referral

This guideline covers the initial assessment of symptoms and signs that might indicate a neurological condition. It helps non-specialist healthcare professionals to identify people who should be offered referral for specialist investigation.

Added 3 months ago

Diagnosis and management of epilepsy in adults

The guideline makes evidence-based recommendations covering all aspects of diagnosis and management of adults with epilepsy including a completely revised section on epilepsy and women’s health and new sections covering...

Added 4 years ago

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Journal articles

Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies.

This review will discuss epigenetic mechanisms implicated in epilepsy development as well as metabolic and biochemical interactions thought to drive epileptogenesis.

Added 1 month ago

Epilepsy in the Elderly: Treatment and Consideration of Comorbid Diseases.

Epilepsy is the third most common neurological disorder affecting older adults after stroke and dementia, and the incidence of epilepsy is increasing rapidly in this population. A further increase in the incidence and prevalence of epilepsy...

Added 1 month ago

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy.

Epilepsy is a chronic neurological disease characterized by an enduring propensity for generation of seizures. The pathogenic processes of seizure generation and recurrence are the subject of intensive preclinical and clinical investigations...

Added 1 month ago

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Clinical trials

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure frequency in participants with pediatric epileptic syndrome...

Added 1 month ago

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

The purpose of the study is to evaluate the efficacy, safety and tolerability of the 3 selected dose regimens of padsevonil (PSL) administered concomitantly with up to 3 anti-epileptic drugs (AEDs) compared with placebo for treatment...

Added 5 months ago

A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy

The XEN1101 Phase 2 clinical trial is a randomized, double-blind, placebo-controlled study that will evaluate the clinical efficacy, safety and tolerability of increasing doses of XEN1101 administered as adjunctive treatment...

Added 1 month ago

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CME

Epilepsy: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
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1
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90

Hallucinations - red flag symptoms

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
0
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1
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0

Epilepsy: clinical review

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
2
Registration required
1
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0
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