Latest news articles

Added 1 day ago Drug news

Acasti Pharma Inc reports results for TRILOGY 1 phase III trial of CaPre for the treatment of severe hypertriglyceridemia .

Acasti Pharma Inc. a biopharmaceutical innovator focused on the research, development and commercialization of its prescription drug candidate CaPre (omega-3...

Added 3 days ago Drug news

Independent Data Monitoring Committee has recommended to discontinue the STRENGTH trial as Epanova is unlikely to demonstrate a benefit. - AstraZeneca.

Following the recommendation from an independent Data Monitoring Committee, AstraZeneca has decided to close the Phase III STRENGTH trial for...

Added 1 month ago Drug news

FDA approves new and expanded indication for Vascepa in patients with elevated triglyceride levels and CV risk.- Amarin

Amarin Corp announced that the FDA has approved a new indication and label expansion for Vascepa (icosapent ethyl) capsules as...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Anticoagulation Therapy for Stroke Prevention

Anticoagulation Therapy for Stroke Prevention

Anticoagulation therapy for Stroke Prevention Learning Zone offers a deep-dive into atrial fibrillation causes, consequences, diagnosis and management to help you deliver optimal care and prevent strokes in patients living with this common arrhythmia.

Acute and Advanced Heart Failure

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Guidelines

Familial hypercholesterolaemia: identifification and management

This guideline covers identifying and managing familial hypercholesterolaemia (FH), a specific type of high cholesterol that runs in the family, in children, young people and adults. It aims to help identify people at increased risk of...

Added 1 month ago

Guidelines for management of dyslipidemia and prevention of atherosclerosis.

The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees.

Added 2 years ago

Cardiovascular disease: risk assessment and reduction, including lipid modification

This guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease and stroke. It aims to help healthcare professionals identify people who are at risk of...

Added 5 years ago

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Journal articles

Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis.

Objective: To evaluate whether baseline LDL-C level is associated with total and cardiovascular mortality risk reductions.

Added 1 year ago

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.

Objective: To evaluate efficacy and safety of further lowering LDL-C levels in patient populations presenting with median LDL-C levels of 1.8 mmol/L (70 mg/dL) or less.

Added 1 year ago

Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy.

In this review, the effect and safety of an approved combination therapy with simvastatin plus fenofibrate are described, with an analysis of pros and cons resulting from randomized multicenter trials, meta-analyses...

Added 1 year ago

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Clinical trials

A Study in Subjects With Type 2 Diabetes Mellitus With Hypercholesterolemia/Mixed Dyslipidemia

The purpose of this study is to evaluate the effect of 12 weeks of subcutaneous evolocumab taken monthly compared with subcutaneous placebo taken monthly on low density lipoprotein cholesterol (LDL-C) in subjects with...

Added 1 year ago

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