Latest news articles

Added 7 hours ago Drug news

FDA accepts BLA for valoctocogene roxaparvovec, for adults with hemophilia A. PDUFA action date is August 21, 2020.- BioMarin

BioMarin Pharmaceutical Inc. announced that the FDA has accepted for Priority Review the Biologics License Application (BLA) to the FDA...

Added 2 months ago Drug news

Sobi reports Republic of Ireland extends supply contract for Elocta to treat haemophilia A

Sobi United Kingdom (UK) and Republic of Ireland (RoI) and the RoI’s ( Republic of Ireland) Haemophilia Product Selection and...

Added 2 months ago Drug news

Additional analyses from phase III study with Doptelet for the treatment of chronic immune thrombocytopenia.- Dova Pharma/Sobi

Dova Pharmaceuticals, a wholly owned subsidiary of Swedish Orphan Biovitrum AB (publ) (Sobi), presented additional analyses from the phase III...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

Optimising anti-TNF treatment using biosimilars

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

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Guidelines

The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition.

Background: Severe traumatic injury continues to present challenges to healthcare systems around the world, and post-traumatic bleeding remains a leading cause of potentially preventable death among injured patients.

Added 2 months ago

BSH Guideline: management of thrombotic and haemostatic issues in paediatric malignancy

Venous thromboembolism (VTE) and bleeding are serious complications of cancer and its treatment. A recent survey of UK paediatric haematologists and oncologists identified a broad variety of practice in the management of issues...

Added 1 year ago

Guidelines for the management of acute joint bleeds and chronic synovitis in haemophilia: A United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO) guideline.

Evidence-based guidelines were developed summarizing best practice for the assessment and management of acute joint bleeds and chronic synovitis in persons with haemophilia.

Added 1 year ago

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Journal articles

Guidance for diagnosis and treatment of DIC from harmonization of the recommendations from three guidelines.

Three guidelines have recently been published for the diagnosis and treatment of disseminated intravascular coagulation (DIC) in adults. This communication seeks to harmonize the recommendations in these guidelines...

Added 2 months ago

Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology.

The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and laboratory information. The International Society for Thrombosis and Haemostasis (ISTH) DIC scoring system provides objective...

Added 2 months ago

The efficacy and safety of cryoprecipitate in the treatment of acquired hypofibrinogenaemia.

Acquired hypofibrinogenaemia can result in haemorrhage and significant morbidity and mortality. Cryoprecipitate is well established as the treatment of acquired hypofibrinogenaemia in the UK.

Added 2 months ago

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Clinical trials

Pregnancy and Fibrinogen Disorders (FIBRINOGEST)

The aim of this observational study is to evaluate the prevalence of uncomplicated pregnancies in women suffering from congenital fibrinogen disorders (i.e, hypofibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia)...

Added 8 months ago

Efficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A Participants (HAVEN 5)

This randomized, multicenter, open-label, Phase 3 study is designed to investigate the efficacy, safety, and pharmacokinetics of emicizumab in participants with hemophilia A regardless of factor VIII (FVIII) inhibitor status.

Added 1 year ago

Adjusted Fibrinogen Replacement Strategy (AdFIrst)

The purpose of this study is to investigate efficacy and safety of fibrinogen concentrate BT524, when administered to patients with major blood loss during elective spine surgery.The study aims to demonstrate that BT524 is at least...

Added 8 months ago

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CME

Dermatological emergencies in children

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MIMS Learning - Monthly Index of Medical Specialities
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Survival guide: safe prescribing for surgical inpatients

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
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1
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90

Starting patients on oral anticoagulants in primary care: how to do it

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
90
Search all CME for Coagulation and haemorrhagic disorders