Added 5 days ago Drug news

Mylan N.V. and Biocon Ltd. announced that the FDA Oncologic Drugs Advisory Committee (ODAC) recommended approval of the companies' proposed biosimilar trastuzumab.

Mylan N.V. and Biocon Ltd. announced that the FDA Oncologic Drugs Advisory Committee (ODAC) recommended approval of the companies' proposed...

Added 1 month ago Drug news

Successful Phase I trial of BLU 285 for gastrointestinal stromal tumors is basis for initiating Phase III trial in 2018.- BluePrint Medicines

Blueprint Medicines Corporation announced new Phase 1 clinical data and outlined registration plans for BLU 285, a potent and highly...

Added 1 month ago Drug news

Findings from Cohort 1 of KEYNOTE-059 trial of Keytruda (pembrolizumab) monotherapy to treat advanced gastric cancer.- Merck Inc.

Merck announced findings from Cohort 1 of the phase II registrational KEYNOTE-059 trial investigating Keytruda (pembrolizumab), the company’s anti-PD-1 therapy,...

Gastric cancer: ESMO–ESSO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best...

Added 3 years ago

Neuroendocrine gastro-entero-pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best...

Added 5 years ago

Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs)

These guidelines update previous guidance published in 2005. They have been revised by a group who are members of the...

Added 5 years ago

The role of BRCA1 and BRCA2 mutations in prostate, pancreatic and stomach cancers.

The association of germline mutations in the breast cancer susceptibility gene 1 (BRCA1) and the breast cancer susceptibility gene 2 (BRCA2) with the development of breast and ovarian...

Added 2 months ago

Helicobacter pylori-induced chronic inflammation causes telomere shortening of gastric mucosa by promoting PARP-1-mediated non-homologous end joining of DNA.

Helicobacter pylori infection leads to chronic gastritis and increased risk of gastric cancer.

Added 10 months ago

Increasing role of the cancer chemotherapeutic doxorubicin in cellular metabolism.

Objectives: The use of doxorubicin, a drug utilised for many years to treat a wide variety of cancers, has long...

Added 1 year ago