Latest news articles

Added 2 days ago Drug news

Surufatinib in advanced neuroendocrine tumors – extra-pancreatic,met the primary endpoint of progression free survival

Hutchison China MediTech announced that the independent Data Monitoring Committee of the Phase III pivotal study of surufatinib in advanced...

Added 13 days ago Drug news

Phase III POLO trial of Lynparza in pancreatic cancer published in NEJM.

AstraZeneca and Merck Inc. announced detailed results from the Phase III POLO trial evaluating Lynparza (olaparib) tablets as a first-line...

Added 3 months ago Drug news

apact study of Abraxane + gemcitabine following surgical resection for pancreatic cancer failed to achieve primary endpoint

The Celgene-sponsored, pivotal, Phase III apact study evaluating the investigational use of Abraxanein combination with gemcitabine following surgical resection (adjuvant...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

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Guidelines

Pancreatic cancer in adults: diagnosis and management

This guideline covers diagnosing and managing pancreatic cancer in adults aged 18 and over. It aims to improve care by ensuring quicker and more accurate diagnosis, and by specifying the most effective treatments...

Added 1 year ago

Cancer of the Pancreas: ESMO Clinical Practice Guidelines

A recent study within Europe reports that pancreatic cancer is the fourth most fatal cancer in men after lung, colorectal, and prostate cancers, and also the fourth most fatal cancer in women after breast, colorectal and lung cancers.

Added 3 years ago

Neuroendocrine gastro-entero-pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Neuroendocrine gastroenteropancreatic tumors (GEP-NETs) constitute a heterogeneous group of tumors with their origin in neuroendocrine cells of the embryological gut. This guideline focuses on diagnosis and pathology/molecular biology...

Added 6 years ago

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Journal articles

Efficacy and Safety of Sunitinib in Patients With Well-Differentiated Pancreatic Neuroendocrine Tumours.

Background: In a phase III study, sunitinib led to a significant increase in progression- free survival (PFS) vs. placebo in patients with pancreatic neuroendocrine tumours (panNETs).

Added 10 months ago

Enhanced recovery after surgery for pancreaticoduodenectomy: Review of current evidence and trends.

Pancreaticoduodenectomy (PD) remains a morbid procedure. The use of Enhanced Recovery After Surgery (ERAS) pathways has proven to reduce care time and post-operative complications after colorectal surgery.

Added 1 year ago

Weekday of cancer surgery in relation to prognosis.

Background: Later weekday of surgery seems to affect the prognosis adversely in oesophageal cancer, whereas any such influence on other cancer sites is unknown. This study aimed to test whether weekday of surgery influenced...

Added 1 year ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.