Latest news articles

Added 2 months ago Drug news

Phase III JAVELIN Gastric 100 study of Bavencio fails to meet endpoint in gastroesophageal junction (GEJ) cancer.- Merck/Pfizer

Merck and Pfizer Inc. announced topline results of the Phase III JAVELIN Gastric 100 study evaluating Bavencio (avelumab) as first-line...

Added 1 year ago Drug news

Eli Lilly to acquire AurKa Pharma and AK 01, an Aurora kinase A inhibitor, in early trials for solid tumours.

Eli Lilly and Company has announced an agreement to acquire AurKa Pharma, Inc., a company established by TVM Capital Life...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.



See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

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Oesophageal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Oesophageal cancer is the 19th most common cancer in Europe and includes two main subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma.

Added 6 years ago

British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus

 These guidelines provide a practical and evidence-based resource for the management of patients with Barrett's oesophagus and related early neoplasia.

Added 6 years ago

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Journal articles

Impact of weight loss and eating difficulties on health-related quality of life up to 10 years after oesophagectomy for cancer.

Severe weight loss is experienced by patients with eating difficulties after surgery for oesophageal cancer. The aim of this prospective cohort study was to asssess the influence of eating difficulties and severe weight loss...

Added 2 years ago

Weekday of cancer surgery in relation to prognosis.

Background: Later weekday of surgery seems to affect the prognosis adversely in oesophageal cancer, whereas any such influence on other cancer sites is unknown. This study aimed to test whether weekday of surgery influenced...

Added 2 years ago

Pragmatic staging of oesophageal cancer using decision theory involving selective endoscopic ultrasonography, PET and laparoscopy.

Background: Following CT, guidelines for staging oesophageal and gastro-oesophageal junction (GOJ) cancer recommend endoscopic ultrasonography (EUS), PET-CT and laparoscopy for T3-T4 GOJ tumours. These...

Added 4 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.


Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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