Data from multiple sources - Curated by Marshall Pearce - Last updated 06 June 2017

Latest news articles

Added 14 days ago Drug news

NICE does not recommend Stivarga as a treatment for liver cancer.- Bayer Healthcare.

The National Institute for Health and Care Excellence (NICE) does not recommend Stivarga (regorafenib) from Bayer HealthCare, as a treatment...

Added 1 month ago Drug news

Phase III CELESTIAL trial of Cabometyx (cabozantinib) meets primary endpoint in advanced hepatocellular carcinoma.- Ipsen + Exelixis.

Ipsen and Exelixis announced that its global phase III CELESTIAL trial met its primary endpoint of overall survival (OS), with...

Added 1 month ago Drug news

FDA grants accelerated approval for Opdivo (nivolumab) to treat hepatocellular carcinoma (liver cancer).- BMS.

Bristol-Myers Squibb Company announced the FDA has approved Opdivo (nivolumab) injection for intravenous use for the treatment of patients with...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.



See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update

CC is the second commonest primary liver tumour worldwide, after hepatocellular carcinoma (HCC). These guidelines are intended to bring consistency...

Added 5 years ago

Erratum to: EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

Fig. 3 was incomplete for BCLC stage A, and it has been corrected as per below. Patients at BCLC stage...

Added 5 years ago

Hepatocellular carcinoma: ESMO–ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best...

Added 5 years ago

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Journal articles

Downstaging therapy followed by liver transplantation for hepatocellular carcinoma beyond Milan criteria.

Background: Orthotopic liver transplantation is a curative treatment for hepatocellular carcinoma within Milan criteria, but these criteria preclude many patients from transplant candidacy.

Added 21 days ago

Liver transplantation in patients with liver metastases from neuroendocrine tumors: A systematic review.

Background: Liver transplantation to treat neuroendocrine tumors, especially in the setting of diffuse liver involvement not amenable to operative resection remains controversial. We sought to perform a systematic review...

Added 21 days ago

Nomograms for prediction of long-term survival in elderly patients after partial hepatectomy for hepatocellular carcinoma.

Background: Partial hepatectomy is an important treatment for elderly patients with hepatocellular carcinoma. However, prediction of long-term outcomes of an individual elderly patient after partial hepatectomy still is lacking.

Added 21 days ago

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Clinical trials

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 13 days ago

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 7 months ago

Efficacy and Tolerability of Hemopatch After Hepatic Resection

• Previous in vitro and in vivo studies detected the Hemopatch Sealing Hemostat® to be a new versatile, self-adhering hemostatic sealing pad consisting of a polyethylene glycol-coated collagen.

Added 13 days ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.