Latest news articles

Added 3 days ago Drug news

Tecentriq fails in Phase III IMvigor010 study as an adjuvant (after surgery) monotherapy compared to observation in people with muscle-invasive urothelial cancer .-Genentech/Roche

Roche announced that the Phase III IMvigor010 study evaluating Tecentriq (atezolizumab) as an adjuvant (after surgery) monotherapy treatment did not...

Added 21 days ago Drug news

Phase III JAVELIN Bladder 100 study met its primary endpoint to treat urothelial carcinoma .- Merck KGaA + Pfizer

Merck and Pfizer Inc. announced the Phase III JAVELIN Bladder 100 study met its primary endpoint of overall survival (OS)...

Added 1 month ago Drug news

FDA Advisory Committee recommends Keytruda for the treatment of certain patients with high-risk, non-muscle invasive bladder cancer (NMIBC).

Merck Inc. announced that the Oncologic Drugs Advisory Committee (ODAC) of the FDA voted 9-4 in favor of recommending Keytruda,...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

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Guidelines

Guidelines on Upper Urinary Tract Urothelial Cell Carcinomas

The European Association of Urology (EAU) Non-muscle-invasive Bladder Cancer (NMIBC) Guidelines Panel has compiled these clinical guidelines to provide urologists...

Added 3 years ago

Guidelines on Non-muscle-invasive Bladder Cancer (Ta, T1 and CIS)

This overview represents the updated European Association of Urology (EAU) Guidelines for Non-muscle-invasive Bladder Cancer (NMIBC), TaT1 and carcinoma in situ (CIS). The information presented is limited to urothelial carcinoma...

Added 3 years ago

Guidelines on Muscle-invasive and Metastatic Bladder Cancer

The European Association of Urology (EAU) Guidelines Panel for Muscle-invasive and Metastatic Bladder Cancer (MIBC) have prepared these guidelines to help urologists assess the evidence-based management of MIBC...

Added 3 years ago

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Journal articles

Diagnostic accuracy of C-11 choline and C-11 acetate for lymph node staging in patients with bladder cancer: a systematic review and meta-analysis.

We aimed to assess the diagnostic accuracy of C-11 choline and C-11 acetate positron emission tomography/computed tomography (PET/CT) for lymph node (LN) staging in bladder cancer (BC) patients through a systematic review...

Added 2 years ago

The anti-PD-1 era - an opportunity to enhance radiotherapy for patients with bladder cancer.

An urgent need exists to improve the outcomes of patients with muscle-invasive bladder cancer (MIBC), and especially of those with metastatic disease. Treatments that enhance antitumour immune responses...

Added 2 years ago

Immunotherapy in metastatic urothelial carcinoma: focus on immune checkpoint inhibition.

Immunotherapy has been used in localized urothelial carcinoma for decades, especially in the treatment of superficial disease, in which instillation of BCG is a commonly used treatment option.

Added 2 years ago

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Clinical trials

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement (HYPALB)

The primary objective of this study is to test the effect of 20% albumin on plasma volume expansion and fluid recruitment in the frame of blood loss replacement during cystectomy using established fluid kinetic models.

Added 10 months ago

Study of Pembrolizumab With or Without Platinum-based Combination Chemotherapy Versus Chemotherapy Alone in Urothelial Carcinoma (MK-3475-361/KEYNOTE-361)

The purpose of this study is to determine the efficacy and safety of pembrolizumab (MK-3475) with or without chemotherapy versus chemotherapy alone in participants with advanced or metastatic urothelial carcinoma (bladder cancer).

Added 1 year ago

Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma (IMvigor130)

A Phase III, randomised study of atezolizumab alone and in combination with chemotherapy versus chemotherapy alone in participants with untreated advanced urothelial cancer.

Added 1 year ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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Union of European Medical Specialists (via European Accreditation Council for CME)
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