Added 3 days ago Drug news

Complete Response Letter for iclaprim to treat acute bacterial skin and skin structure infections.- Motif Bio

Motif Bio plc announced that the Company has received a Complete Response Letter (CRL) from the FDA regarding the New...

Added 10 days ago Drug news

Phase III OPTIC/OASIS-1 trials of Nuzyra in CABP and ABSSSI published in New England Journal of Medicine.- Paratek Pharma

Paratek Pharmaceuticals announced The New England Journal of Medicine (NEJM) published detailed results from the OPTIC and OASIS-1 Phase III...

Added 12 days ago Drug news

MK 7655 + Primaxin + cilastatin filed with FDA for cUTI + cIAI.- Merck Inc

Merck Inc. announced that the FDA has accepted for review regulatory filings for Priority Review for the combination of MK...

Guidelines on Urological Infections

The European Association of Urology (EAU) Urological Infections Guidelines Panel has compiled these clinical guidelines to provide medical professionals with evidence-based information and recommendations for...

Added 2 years ago

The Prevention of Early-onset Neonatal Group B Streptococcal Disease

The purpose of this guideline is to provide guidance for obstetricians, midwives and neonatologists on the prevention of early-onset (less than 7 days of age) neonatal group B streptococcal (EOGBS) disease...

Added 6 years ago

Fever in under 5s: assessment and initial management

This guideline covers the assessment and early management of fever with no obvious cause in children aged under 5.

Added 5 years ago

Pseudomonas aeruginosa in cystic fibrosis patients with c.1652G›A (G551D)-CFTR treated with ivacaftor-Changes in microbiological parameters.

The CFTR potentiator, ivacaftor (IVA), has been widely used in the treatment of cystic fibrosis (CF) patients with the G551D mutation. To date, there has been limited information on the microbiological status...

Added 1 year ago

Early goal-directed therapy in the treatment of severe sepsis and septic shock.

Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit.

Added 1 year ago

Early, goal-directed therapy for septic shock – a patient-level meta-analysis.

After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septicshock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit.

Added 1 year ago