Latest news articles

Added 1 month ago Drug news

Phase III trials of E 2609 for Alzheimers will be discontinued

Eisai Co and Biogen announced the decision to discontinue the Phase III clinical studies (MISSION AD1, AD2) on the investigational...

Added 3 months ago Drug news

Amgen, Novartis And Banner Alzheimer's Institute discontinue clinical research program With CNP 520 For Alzheimer's Prevention

Amgen, Novartis and Banner Alzheimer's Institute announced the collective decision to discontinue investigation of the BACE1 inhibitor CNP 520 (umibecestat)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Delirium: prevention, diagnosis and management

This guideline covers diagnosing and treating delirium in people aged 18 and over in hospital and in long-term residential care or a nursing home. It also covers identifying people at risk of developing delirium in these settings and...

Added 2 months ago

Risk reduction and management of delirium

This guideline provides recommendations based on current evidence for best practice in the detection, assessment, treatment and follow up of adults with delirium, as well as reducing the risk of delirium.

Added 1 month ago

Dementia: assessment, management and support for people living with dementia and their carers

This guideline covers diagnosing and managing dementia (including Alzheimer’s disease). It aims to improve care by making recommendations on training staff and helping carers to support people living with dementia.

Added 2 months ago

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Journal articles

Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment.

Objective: To assess the association between alcohol consumption and dementia and the roles of mild cognitive impairment (MCI) and apolipoprotein E ε4 (APOE E4) genotype in modifying this association.

Added 13 days ago

Treatment for depression comorbid with dementia.

Depression is a common comorbidity in dementia. Randomised controlled studies of antidepressants do not show a significant improvement in depressive symptoms in patients with comorbid dementia and are known to lead to an increase in...

Added 13 days ago

Targeted metabolomic analysis of nitric oxide/L-arginine pathway metabolites in dementia: association with pathology, severity, and structural brain changes.

L-Arginine/NO pathway is altered in Alzheimer disease (AD). Its clinical relevance and pathway status in vascular dementia (VaD) are unknown. Using targeted metabolomics (a liquid chromatography-mass spectrometry) we assessed...

Added 13 days ago

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Clinical trials

PTI-125 for Mild-to-moderate Alzheimer's Disease Patients

This is a Phase 2b, Randomized, Double-blind, Placebo-controlled, multiple dose study of PTI-125 in mild-to-moderate Alzheimer's disease patients. A total of sixty (60) patients will be enrolled in the study.

Added 13 days ago

Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia

Butylphthalide soft capsule has been confirmed to have beneficial effects for patients with vascular dementia (VaD) in clinical trial of phase II study. So the investigators hypothesize that Butylphthalide soft capsule may have same beneficial...

Added 4 months ago

GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease

This is a randomized, double-blind, placebo-controlled study that will assess the efficacy, safety, and tolerability of 2 dose levels of COR388 in subjects with a clinical diagnosis of mild to moderate AD dementia.

Added 5 months ago

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Dr Cornelia Meisenberg

Dr Conny Meisenberg is a medical writer at EPG Health. She joined EPG Health in 2019 following 7 years of postdoctoral research in the oncology field.

Progressive Supranuclear Palsy (PSP)

What is Progressive Supranuclear Palsy (PSP)? Review the causes, treatment and current trials for this uncommon, degenerative disorder.

CME

Diabetes care, antivirals for flu and dementia risk: update clinical February 2016

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Hallucinations - red flag symptoms

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Alzheimer's disease: clinical review

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