Acute myocardial infarction homepage

Analysis of phase III DECLARE-TIMI 58 trial showed that Farxiga reduced the risk of adverse CV events

Positive results from a pre-specified sub-analysis of the Phase III DECLARE-TIMI 58 trial showed that Farxiga (dapagliflozin) from AstraZeneca, reduced...

Added 1 month ago Drug news

EC approves Praluent for CV risk in adults with CV disease

The European Commission (EC) has approved a new indication for Praluent (alirocumab), from Sanofi + Regeneron, to reduce cardiovascular (CV)...

Added 2 months ago Drug news

FDA approves MANTA Vascular Closure Device for large bore femoral arterial access.- . Teleflex

Teleflex Incorporated has announced that it received premarket approval (PMA) from the FDA for the MANTA Vascular Closure Device –...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

ESICM LIVES Highlights

ESICM LIVES Congress 2018: Bringing you the latest news and insights from the 31^st ESICM LIVES Congress, 20–24 October 2018 Paris, France.

Guidelines

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

The management of acute myocardial infarction continues to undergo major changes. Good practice should be based on sound evidence, derived from well-conducted clinical trials.

Added 6 years ago

Chest pain of recent onset: assessment and diagnosis

This guideline covers assessing and diagnosing recent chest pain in people aged 18 and over and managing symptoms while a diagnosis is being made.

Added 9 years ago

Acute coronary syndrome

This guideline provides recommendations for the management of patients with ACS within the first 12 hours and up to hospital discharge.

Added 1 year ago

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Journal articles

Migraine and cardiovascular disease: systematic review and meta-analysis.

Objective: To evaluate the association between migraine and cardiovascular disease, including stroke, myocardial infarction, and death due to cardiovascular disease.

Added 21 days ago

Migraine and the risk of cardiovascular and cerebrovascular events: a meta-analysis of 16 cohort studies including 1 152 407 subjects.

Objectives: To perform an updated meta-analysis to evaluate the long-term cardiovascular and cerebrovascular outcomes among migraineurs.

Added 28 days ago

Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors.

Background: Although factor Xa inhibitors have become a popular choice for chronic oral anticoagulation, effective drug reversal remains difficult due to a lack of specific antidote.

Added 8 months ago

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Clinical trials

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease (COMPASS)

The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death...

Added 7 years ago

An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome

The purpose of this study is to determine whether rivaroxaban in addition to standard care reduces the risk of the composite of cardiovascular death, myocardial infarction, or stroke in patients...

Added 1 year ago

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Peter English

Doctor in public health and health protection. Particular interests in vaccination (editor of journal Vaccines in Practice) and health informatics/intelligence. I blog and post in a personal capacity: nothing I write here should be assumed to represent the views of anybody other than ... Read more

The advance decision not to attempt cardiopulmonary resuscitation

Decisions to start cardiopulmonary resuscitation (CPR), or to decide in advance to issue a "do not attempt (cardiopulmonary) resuscitation" (DNAR) notice have always been a hot topic in clinical medicine. It may have become even more so since a recent (June 2014) court decision. This post discusses some of the issues and legalities around DNAR decisions.