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Latest news articles

Added 11 hours ago Drug news

Two analyses show benefits of Xarelto for patients with PAD and CAD.- Bayer + Janssen.

Two new analyses of data from the COMPASS trial show that Xarelto (rivaroxaban),from Bayer and Janssen ,significantly cut the amputation...

Added 11 hours ago Drug news

FDA approves remote programming via telemedicine of Nucleus Cochlear Implant System.- Cochlear Corporation.

The FDA has approved a remote feature for follow-up programming sessions for the Nucleus Cochlear Implant System, from Cochlear Corporation,...

Added 11 hours ago Drug news

Acorda Therapeutics increases blood cell monitoring in Phase III programme for tozadenant for Parkinson’s disease.

Acorda Therapeutics, Inc. announced that it has increased the frequency of blood cell count monitoring for participants to weekly in...

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What's on the horizon?

Marshall Pearce

Cancer immunotherapies

Posted 6 months ago

It was the winner of the 1908 Nobel prize for medicine, Paul Ehrlich, who is first credited with discussing the concept of a “magic bullet”, able to target specific cells without damaging healthy tissue. With the advent of immunotherapy, as well as antibody-drug conjugates, we are beginning to realise this vision.

Marshall Pearce

Antibody-drug conjugates (ADCs)

Posted 7 months ago

Over the past couple of decades, there have been advances in a class of drugs which for a long time was purely theoretical: antibody-drug conjugates (ADCs). The concept underlying ADCs is elegant – what if it were possible to ‘target’ particular groups of cells with a cytotoxic agent, rather than exposing every cell of the body to it?

Latest Clinical Trials

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer (EarLEE-2)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 5 days ago

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 9 days ago

Multiple Cardiac Sensors for the Management of Heart Failure (MANAGE-HF)

The MANAGE-HF study is a multi-center, global, prospective, open label, multi-phase trial intended to evaluate the clinical efficacy of the HeartLogic heart failure diagnostic feature.

Added 1 month ago

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Latest Journal Abstracts

Schizophrenia relapse, patient considerations, and potential role of lurasidone.

When treating persons with schizophrenia, delaying time to relapse is a main goal. Antipsychotic medication has been the primary treatment approach, and there are a variety of different choices available.

Added 2 days ago

Weight changes before and after lurasidone treatment: a real-world analysis using electronic health records.

Background: Severe and persistent mental illnesses, such as schizophrenia and bipolar disorder, are associated with increased risk of obesity compared to the general population. While the association of lurasidone and lower risk...

Added 2 days ago

Aripiprazole and impulse control disorders: higher risk with the intramuscular depot formulation?

Dopamine agonists have been associated with an increased risk of developing impulse control disorders (ICDs). The US Food and Drug Administration (FDA) issued a safety warning in 2016 of a possible association between ICDs and aripiprazole.

Added 2 days ago

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Latest Guidelines

The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Acute and longterm treatment of mixed states in bipolar disorder

This WFSBP guideline has been developed to supply a systematic overview of all scientific evidence pertaining to the acute and longterm treatment of bipolar mixed states in adults.

Added 10 days ago

Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Evidence shows that rectal cancer is distinct from colon cancer, with different aetiologies and risk factors possibly reflecting different environmental exposures.

Added 4 years ago

Cervical cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Cervical cancer is the second most commonly diagnosed cancer and the third leading cause of cancer death among females in less developed countries. These updated guidelines focus on the management...

Added 5 years ago

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