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Latest News

Added 11 hours ago Drug news

EU Commission approves Kyntheum (brodalumab) of moderate-to-severe plaque psoriasis.- Leo Pharma

AstraZeneca and MedImmune, announced that its partner Leo Pharma has been granted full marketing authorisation in all 28 EU member...

Added 11 hours ago Drug news

Rolling submission to FDA started for CAM 2038 (buprenorphine depots) in Opioid Use Disorder- Braeburn Pharmaceuticals and Camurus

Braeburn Pharmaceuticals and Camurus announced the completion of the rolling submission of a New Drug Application (NDA) to the U.S....

Added 11 hours ago Drug news

Study suggests Reminyl XL/Razadyne (galantamine hydrobromide) provides benefits in metabolic syndrome- Janssen Pharma

Alzheimer's medication Reminyl XL/Razadyne (galantamine hydrobromide) from Janssen Pharma, appears to slash inflammation and insulin resistance in patients with metabolic...

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What's on the horizon?

Marshall Pearce

Cancer immunotherapies

Posted 3 months ago

It was the winner of the 1908 Nobel prize for medicine, Paul Ehrlich, who is first credited with discussing the concept of a “magic bullet”, able to target specific cells without damaging healthy tissue. With the advent of immunotherapy, as well as antibody-drug conjugates, we are beginning to realise this vision.

Marshall Pearce

Antibody-drug conjugates (ADCs)

Posted 3 months ago

Over the past couple of decades, there have been advances in a class of drugs which for a long time was purely theoretical: antibody-drug conjugates (ADCs). The concept underlying ADCs is elegant – what if it were possible to ‘target’ particular groups of cells with a cytotoxic agent, rather than exposing every cell of the body to it?

Latest Clinical Trials

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 3 months ago

A Three-part Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of Secukinumab Treatment in Juvenile Idiopathic Arthritis Subtypes of Psoriatic and Enthesitis-related Arthritis

This is a double-blind, placebo-controlled, event-driven randomized withdrawal study to investigate the efficacy and safety of secukinumab treatment in the Juvenile Idiopathic Arthritis (JIA)...

Added 5 months ago

Post-Marketing Surveillance of Adalimumab in Korean Hidradenitis Suppurativa Subjects (HS rPMS)

The objective of this study is to evaluate the safety profile of Adalimumab for Hidradenitis Suppurativa (HS) participants in normal medical practice.

Added 5 months ago

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Latest Journal Abstracts

Treating tobacco dependence: guidance for primary care on life-saving interventions. Position statement of the IPCRG.

Tobacco smoking is the world's leading cause of premature death and disability. Global targets to reduce premature deaths by 25% by 2025 will require a substantial increase in the number of smokers making a quit attempt...

Added 10 hours ago

Abiraterone for prostate cancer not previously treated with hormone therapy

Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate cancer.

Added 4 days ago

Causal relationship between hypoalbuminemia and acute kidney injury.

Our meta-analysis published in 2010 provided evidence that low levels of serum albumin (hypoalbuminemia) are a significant independent predictor of acute kidney injury (AKI) and death following AKI.

Added 4 days ago

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Latest Guidelines

American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia and prevention of atherosclerosis.

The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees.

Added 4 months ago

GOLD 2017 Global Strategy for the Diagnosis, Management and Prevention of COPD.

Since 2001, the Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease has been a valuable resource for healthcare professionals.

Added 2 months ago

Psoriasis overview NICE Pathways

This document contains a single pathway diagram and uses numbering to link the boxes to the associated recommendations.

Added 5 months ago

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