Disease Awareness

The Disease Awareness section aims to provide accurate information on the clinical manifestations and diagnosis of cystic fibrosis. This section also looks at the comorbidities that a patient may encounter. Click on the links below to find out more about cystic fibrosis and how it affects patients. 

This Knowledge Centre and all of the subsequent sections have been independently reviewed for clinical accuracy by Prof. Isabelle Fajac, MD, PhD (January 2017). Click here to read her short biography. 

 

Epidemiology

Epidemiology

Read about the epidemiology of Cystic Fibrosis in Europe, including prevalence and incidence of disease depending on factors such as ethnicity.

Clinical Manifestations

Clinical Manifestations

Explore the various clinical manifestations of cystic fibrosis, including gastrointestinal and pulmonary disease.

Comorbidities

Comorbidities

Learn about the wide range of comorbidities that are associated with cystic fibrosis such as diabetes and infertility.

Genetics and Proteins

Genetics and Proteins

Read about the role that the CFTR gene plays in normal cell physiology.

Airway Pathophysiology

Airway Pathophysiology

Discover how CFTR mutations can cause airway dysfunction and what kind of effect these mutations can have.

Diagnosis

Diagnosis

Learn what diagnostic tests are available to diagnose cystic fibrosis in children and newborns, such as the sweat test and CFTR genotyping.