Adrenocortical carcinoma (ACC) is a rare, aggressive endocrine malignancy arising from the adrenal cortex. It is a progressive disease associated with a poor prognosis. Most of patients (~2/3) symptoms are due to signs of hormone excess. Hypercortisolism is the most common case (50%–80%) which gives rise to rapidly developing Cushing’s syndrome (Else et al., 2014). This learning resource will enable you to understand the symptoms of ACC, and the key recommendations for clinical assessment, detailed hormonal work-up, imaging, pathological work-up, and staging classification and prognostic factors.
What is adrenocortical carcinoma? View the key facts, clinical presentation and prognosis.
This section details the key recommendations of the European Society of Endocrinology (ESE).
Review treatment recommendations are based on whether ACC is localised or advanced.
Associations, societies and patient support groups to help further your knowledge and understanding of adrenocortical carcinoma.