Associate Professor Christian Vestergaard addresses the role of topical steroids in chronic spontaneous urticaria, answering the question 'Are topical treatments such as topical corticosteroids recommended in chronic spontaneous urticaria?'.
The short answer to this question is no.1 Topical corticosteroids have been tested in experimental human wheals induced by prick testing with histamine. The results are conflicting but, in conclusion, topical steroids are not very effective.2 A few studies on topical corticosteroids in delayed pressure urticaria have shown some effect and in this instance occlusive treatment may have an effect.3
Topical corticosteroids are used in many inflammatory skin diseases including atopic dermatitis. The inflammatory reaction in atopic dermatitis may, in part, be due to mast cell induction of wheals. Treatment with topical steroids in this situation may have a beneficial effect on the wheals, but this is due to decreased inflammation in the skin.
Associate Professor, Department of Dermatology, University of Aarhus, Denmark.
Christian Vestergaard, Associate Professor in the Department of Dermatology at the University of Aarhus, Denmark answers the question, 'How should the UAS7 be used in chronic spontaneous urticaria?'.
Werner Aberer, Professor of Dermatology and Chairman at the Department of Dermatology, Medical University of Graz, Austria answers the question 'When a patient has been started on omalizumab, can you stop antihistamine treatment?'.
Karoline Krause, Assistant Professor of Dermatology at the Department of Dermatology and Allergy, Charité – Universitätsmedizin Berlin, Germany, is posed the question: 'Do IgE levels need to be measured before starting a patient with chronic spontaneous urticaria on omalizumab?'.
Doctor Marta Ferrer of Clínica Universidad de Navarra, Pamplona, discusses how pregnancy affects treatment options for CSU, answering the question, 'Can chronic spontaneous urticaria be treated during pregnancy?'.
Professor Ana Giménez-Arnau, Professor of Dermatology at the Hospital del Mar, Universitat Autònoma, Barcelona discusses how to choose a third-line treatment in a patient who has not responded to antihistamine treatment.
Professor Martin Metz of University Hospital Charité, Berlin discusses when to consider withdrawing treatment in those who no longer have symptoms, answering the question 'When should you stop treating a patient with CSU?'.
Professor Aberer of the University of Graz answers the question of which antihistamine to choose in a newly diagnosed patient with CSU, discussing the benefits of second-generation antihistamines and dosing strategies.
Associate Professor Emek Kocatürk discusses the investigations that should be carried out when seeing a patient with new onset chronic spontaneous urticaria.
Our expert, Associate Professor Emek Kocatürk, answers the question of what differential diagnoses to consider when confronted with a patient presenting with symptoms of CSU, explaining how to exclude these through a mixture of clinical and laboratory tests.
Take a look at some of the frequently asked questions about the low-pseudoallergen diet, answered by our expert Josefine Grünhagen. Including the effects of pre-cooking meals and the use of raising agents in bread and eggs in cakes.
Josefine Grünhagen discusses the use of low-pseudoallergen diets in relation to patients with chronic spontaneous urticaria symptoms.