International Guidelines

The Need for International Guidelines in Urticaria

Clinical decisions regarding the best diagnostic and therapeutic approaches in patients with urticaria can vary from one allergist or dermatologist to another, and between clinical centres. International guidelines offer clear evidence-based recommendations that:

  • Clarify which interventions are of proven benefit
  • Document the quality of the supporting data
  • Take into consideration regional differences in causative factors, medical systems and access to diagnosis and treatment worldwide

The 2017 International EAACI/GA2LEN/EDF/WAO Urticaria Guidelines

The only international recommendations for the diagnosis and management of urticaria are provided by the EAACI/GA²LEN/EDF/WAO urticaria guidelines (Zuberbier et al., 2017).

The 2017 International EAACI/GA2LEN/EDF/WAO urticaria guidelines are:

  • A joint initiative of four societies: the European Academy of Allergy and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA2LEN), the European Dermatology Forum (EDF) and the World Allergy Organization (WAO)
  • The result of a systematic literature review using a modified version of the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system and outcomes from a consensus conference on the 1 December  2016, with 44 urticaria experts from 25 countries

The 2017 revision and update to the international EAACI/GA2LEN/EDF/WAO urticaria guidelines include evidence-based recommendations for the definition, classification, diagnosis and management of urticaria (Zuberbier et al., 2018).

Table 3. Summary of the updated 2017 international EAACI/GA2LEN/EDF/WAO urticaria guidelines

Summary of the updated 2017 international EAACI/GA2LEN/EDF/WAO urticaria guidelines.