• Montse Alvaro


Name: Mª Montserrat Alvaro Lozano

Present Position: Consultant at Pediatric Allergy and Clinical Immunology Department. Hospital Sant Joan de Déu. Universitat de Barcelona. Esplugues, Barcelona.

Professional Address: Secció d’Al.lèrgia i Immunologia clinica. HOSPITAL SANT JOAN DE DÉU. Universitat de Barcelona. Passeig de Sant Joan de Déu , 2. Esplugues 08950. SPAIN.

ACADEMIC AND PROFESSIONAL TRAINING:

- Degree in Medicine by Universitat Autónoma de Barcelona in 1981.
- Pediatric specialist from 1986.
- Master in Clinical Immunology and Pediatric Allergy . Universitat de Barcelona. 1996.
- Doctor in Medicine and Surgery by Universitat de Barcelona. Degree “Cum Laude” with the These “Adhesion molecules and respiratory function study in acute and chronic asthma. It’s utility in the detection of pediatric asthma chronification”. 2002.
- Acreditation in Paediatric Allergy and Clinical Immunology by the Spanish Pediatric Association. 2006.
- EUROPEAN PEDIATRIC ALLERGIST by the European Academy of Allergy and Clinical Immunology (EAACI). 2006.
- Chair of the Pediatric Board of the “European Academy of Allergology and Clinical Immunology” (EAACI).
-Member of the Immunotherapy Committee  of the “Sociedad Española de Inmunología Clínica y Alergia Pediátricas” (SEICAP).
-Member of the Dermatology Committee  of the “Sociedad Española de Inmunología Clínica y Alergia Pediátricas” (SEICAP).
- Member of the Dermatology Committee  of  Societat Catalana d’Al.lèrgia i Immunologia Clínica (SCAIC).
-Reference Centre and Pediatric Allergist for Chronic Urticaria in the area of Barcelona.

SOCIETIES MEMBERSHIP:

- European Academy of Allergy and Clinical Immunology (EAACI).
- Sociedad Española de Inmunología Clínica y Alergia Pediátrica (SEICAP).
- Asociación Española de Pediatría (AEP).
- Societat Catalana d’Al.lèrgia i Immunologia Clínica (SCAIC).
- Sociedad Española de Alergia y Inmunologia Clinica (SEAIC)
- Associate editor of  “Clinical and Traslational Allergy” (CTA).
- Editorial Board member in “Pediatric Allergy and Immunology” (PAI). 
- Invited editor of “Pediatric Allergy and Immunology” (PAI).
- Reviewer for: Journal of Allergy and Clinical Immunology,  Journal of Allergy and Clinical Immunology in practice, Clinical and Experimental Allergy,  Allergy, Paediatric Allergy and Immunology, Allergologia et Immunopathologia. 

LATEST PUBLICATIONS:

-Cow's milk protein allergy. A multi-centre study: clinical and epidemiological aspects.
Antonio Martorell, Ana María Plaza, Javier Boné, Santiago Nevot, M Carmen García Ara, Luis Echeverria, Elena Alonso, Jesús Garde, Blanca Vila, Montserrat Alvaro, Eulalia Tauler, Vicente Hernando, Margarita Fernández
Allergologia et Immunopathologia 01/2006; 34(2):46-53. 

-Diagnosis and treatment of allergic rhinitis in children: results of the PETRA study.
M Ibero, J L Justicia, M Alvaro, O Asensio, O Domínguez, J Garde, J Sancha, A Valero
Allergologia et Immunopathologia 04/2011; 40(3):138-43.

-Allergic reactions due to cow’s milk (CM) doses and triggering factors in 40 CM anaphylactic children during maintenance phase of specific oral tolerance induction (SOTI) treatment to CM in our unit
Marta Vazquez, Jaime Lozano, Rosa Jimenez, Montserrat Alvaro, Olga Dominguez, Ana Maria Plaza
08/2011; 1(1). DOI:10.1186/2045-7022-1-S1-O47

-Specific oral desensitization in children with IgE-mediated cow’s milk allergy. Evolution in one year.
Alvaro M, Giner MT, Vazquez M, Lozano J, Dominguez O, Piquer M, Días M, Jiménez R, Martín MA, Alsina L, Plaza AM.
European Journal of pediatrics , vol 171, nº 9 (2012), pag 1389-1395.
DOI: 10.1007/s00431-012-1739-z

-Reply to correspondence letter by M. Korppi.
Montserrat Alvaro, Ma Teresa Giner, Marta Vázquez, Jaime Lozano, Olga Domínguez, Mónica Piquer, Marcia Días, Rosa Jiménez, Ma Anunciación Martín, Laia Alsina, Ana Ma Plaza
European Journal of Pediatrics 11/2012. DOI:10.1007/s00431-012-1877-3.

A 10% liquid immunoglobulin preparation for intravenous use (Privigen(®)) in paediatric patients with primary immunodeficiencies and hypersensitivity to IVIG.
J Lozano-Blasco, M A Martín-Mateos, L Alsina, O Domínguez, M T Giner, M Piquer, M Alvaro, A M Plaza
Allergologia et Immunopathologia 12/2012; DOI:10.1016/j.aller.2012.10.006 · 

-Moderate persistent asthma and high casein-IgE predict adverse events during oral immunotherapy for milk allergy.
Vazquez M, Alvaro M, Alsina L, Garcia-Paba MB, Piquer M, Giner MT, Lozano J, Domínguez O, Jiménez R, Días M, Martín-Mateos MA, Plaza AM. 
Clinical and Experimental Allergy. CEA-2012-0283-ROH.R1.

-Allergen specific immunotherapy:update on immunological mechanisms.
Alvaro M,  Sancha J, Larramona H, Lucas JM, Mesa M, Tabar AI, Martínez-Cañavate A.
Immunotherapy working group. SEICAP.
Allergol Immunopathol (Madrid). 2012. http://dx.doi.org/10.1016/j.aller.2012.07.018

-Safety and predictors of adverse events during oral immunotherapy for milk allergy: severity of reaction at oral challenge, specific IgE and prick test.
M Vázquez-Ortiz, M Alvaro-Lozano, L Alsina, M B Garcia-Paba, M Piquer-Gibert, M T Giner-Muñoz, J Lozano, O Domínguez-Sánchez, R Jiménez, M Días, M A Martín-Mateos, A M Plaza-Martín
Clinical & Experimental Allergy 01/2013; 43(1):92-102. DOI:10.1111/cea.12012 ·

-Safety and predictors of adverse events during oral immunotherapy with raw egg white
M Vazquez-Ortiz, M Alvaro, O Dominguez, R Jimenez-Feijoo, MT Giner, MA Martin-Mateos, AM Plaza
07/2013; 3(3). DOI:10.1186/2045-7022-3-S3-O26

-Gad c 1 efficiency in the diagnosis of fish allergy in children
O Domínguez, P Carrillo, M Giner, M Piquer, M Alvaro, R Jimenez-Feijoo, J Lozano, M Pascal, A Plaza
07/2013; 3(3). DOI:10.1186/2045-7022-3-S3-P54

-Usefulness of the ratio total IgE / specific IgE (sIgE) to predict tolerance in children allergic to cow's milk proteins (CMP)
A Machinena, M Alvaro, J Lozano, M Piquer, O Dominguez, AM Plaza, MT Giner
07/2013; 3(3). DOI:10.1186/2045-7022-3-S3-P101

-Baseline specific IgE levels are useful to predict safety of oral immunotherapy in egg-allergic children.
M Vazquez-Ortiz, M Alvaro, M Piquer, O Dominguez, A Machinena, M A Martín-Mateos, A M Plaza
Clinical & Experimental Allergy 01/2014; 44(1):130-41. DOI:10.1111/cea.12233 · 4.32 Impact Factor

 -Is other bovid mammals milk tolerated by children who have been submitted to cow's milk oral immunotherapy?
Mònica Piquer Gibert, Spera Adriana Machinena, Montserrat Alvaro Lozano, Maria Teresa Giner Muñoz, Olga Domínguez Sánchez, Jaime Lozano Blasco, Ana Maria Plaza Martin
01/2014; 4(Suppl 1 3rd Pediatric Allergy and Asthma Meeting (PAAM)Publi):P28. DOI:10.1186/2045-7022-4-S1-P28

-Tolerance To Egg Proteins In Egg Sensitized Infants Without Previous Consumption
Montserrat Álvaro, Beatriz García‐Paba, Teresa Giner, Mónica Piquer, Olga Domínguez, Jaime Lozano, Rosa Jiménez, Adrianna Machinena, M.A. Martín‐Mateos, Ana M Plaza
Allergy 07/2014; 69(10). DOI:10.1111/all.12483 ·

-Predicting reactions severity at challenge in egg allergic patients
Marta Vazquez-Ortiz, Alvaro M, Piquer M, Dominguez O, Machinena A, Martín-Mateos MA, Plaza AM
Clinical & Experimental Allergy 08/2014; doi: 10.1111/cea.12364.(8). DOI:10.1111/cea.12364 ·

-Life-threatening anaphylaxis to egg and milk oral immunotherapy in asthmatic teenagers
Marta Vazquez-Ortiz, Montserrat Alvaro, Mónica Piquer, María Teresa Giner, Olga Dominguez, J Lozano, Rosa Jiménez-Feijoo, Francisco José Cambra, Ana María Plaza
Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology 08/2014; 113(4). DOI:10.1016/j.anai.2014.07.010 ·

-Can total IgE/specific IgE ratio predict tolerance in cow's milk allergic children?
A Machinena-Spera, M T Giner-Muñoz, M Alvaro-Lozano, R Iniesta-Benedicto, J Lozano-Blasco, M Piquer-Gibert, I Ferrer-Codina, O Dominguez-Sanchez, R Jimenez Feijoo, A M Plaza-Martin
Pediatric Allergy and Immunology 09/2014; DOI:10.1111/pai.12278 ·

-Impact of oral immunotherapy on quality of life in egg allergic children
M Vazquez-Ortiz, M Alvaro, M Piquer, O Dominguez, Mt Giner, J Lozano, R Jiménez-Feijoo, Am Plaza
Pediatric Allergy and Immunology 02/2015; DOI:10.1111/pai.12355 · 

-Oral immunotherapy in food allergy: Present and future.]
M Alvaro, A Muraro
Anales de Pediatria. DOI: 10.1016/j.anpedi.2014.12.019.

- Evidence in immunotherapy for paediatric respiratory allergy: Advances and recommendations. Document of the Immunotherapy.Working Group of the Spanish Society of Pediatric Clinical Immunology and Allergology (SEICAP)
M. Tortajada-Girbés, M. Mesa del Castillo, H. Larramona, J.M. Lucas, M. Álvaro, A.I. Tabar, M.J. Jerez, A. Martínez-Cañavate
Allergol Immunopathol (Madr). 2016;44(S1):1--32

-Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review
Sangeeta Dhami, Ulugbek Nurmatov, Giovanni Battista Pajno, Montserrat Fernandez‐Rivas, Antonella Muraro, Graham Roberts, Cezmi Akdis, Montserrat Alvaro‐Lozano, Kirsten Beyer, Carsten Bindslev‐Jensen, Wesley Burks, George du Toit, Motohiro Ebisawa, Philippe Eigenmann, Edward Knol, Mika Makela, Kari Christine Nadeau, Liam O’Mahony, Nikolaos Papadopoulos, Lars Poulsen, Cansin Sackesen, Hugh Sampson, Alexandra Santos, Ronald van Ree, Frans Timmermans and Aziz Sheikh.
Clin Transl Allergy (2016) 6:24 DOI 10.1186/s13601-016-0113-z

- Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis.
Nurmatov U, Dhami S, Arasi S, Pajno GB, Fernandez-Rivas M, Muraro A, Roberts G, Akdis C, Alvaro-Lozano M, Beyer K, Bindslev-Jensen C, Burks W, du Toit G, Ebisawa M, Eigenmann P, Knol E, Makela M, Nadeau KC, O'Mahony L, Papadopoulos N, Poulsen LK, Sackesen C, Sampson H, Santos AF, van Ree R, Timmermans F, Sheikh A.
Allergy. 2017 Aug;72(8):1133-1147. doi: 10.1111/all.13124. Epub 2017 May 11.

- Food protein-induced enterocolitis syndrome to fish and egg usually resolves by age 5 years in Spanish children.
Marta Vazquez-Ortiz, MD, PhDa,b, Adrianna Machinena, MDa, Olga Dominguez, MDa, Montserrat Alvaro, MD, PhDa, Katty Calvo-Campoverde, MDa, María Teresa Giner, MDa, Rosa Jiménez-Feijoo, MD, PhDa, Jaime Lozano, MDa, Mònica Piquer, MDa, Marcia Dias, MDa, María del Mar Folqué, MDa, Ana María Plaza, MD, PhD
The Journal of Allergy and Clinical Immunology: In Practice JAIP1025PII:S2213219817300132DOI:10.1016/j.jaip.2016.12.029.

-EAACI Guidelines on Allergen Immunotherapy: IgE-mediated Food Allergy.
Giovanni B. Pajno, Montserrat Fernandez-Rivas, Stefania Arasi,  Graham Roberts, Cezmi Akdis, Montserrat Alvaro-Lozano, Kirsten Beyer, Carsten Bindslev-Jensen, Wesley Burks, Motohiro Ebisawa, Philippe Eigenmann, Edward Knol, Kari C. Nadeau, Lars K. Poulsen, Ronald van Ree, Alexandra F. Santos,  George du Toit,  Sangeeta Dhami, Ulugbek Nurmatov, Yanne Boloh, Mika Makela, Liam O’Mahony Nikolaos Papadopoulos, Cansin Sackesen, Ioana Agache, Elizabeth Angier, Susanne Halken, Marek Jutel, Susanne Lau, Oliver Pfaar, Dermot Ryan, Gunter Sturm, Eva-Maria Varga, Roy Gerth van Wijk, Aziz Sheikh, and Antonella Muraro, on behalf of EAACI Immunotherapy Guidelines Group. Allergy, 2018.

Clinical trials in allergen immunotherapy: Current concepts and future needs. February 2018 Allergy 73(9). DOI: 10.1111/all.13429. O.Pfaar, Montserrat Alvaro, Victòria Cardona et al. 

‘Real-life’ experience in asthmatic children treated with omalizumab up to six-years follow-up. November 2018, Allergologia et Immunopathologia. DOI: 10.1016/j.aller.2018.09.009. M.M. Folqué, Jaime Lozano, C. Riggioni, M. Alvaro, et al. 

Allergen Immunotherapy for IgE‐Mediated Food Allergy: there is a measure in everything to a proper proportion of therapy. February 2019, Pediatric Allergy and Immunology, DOI: 10.1111/pai.13042. Giovanni Battista Pajno, Riccardo Castagnoli, Antonella Muraro, M. Alvaro, et al. 

Severe asthma: entering an era of new concepts and emerging therapies: Highlights of the 4th International Severe Asthma Forum, Madrid, 2018. April 2019, Allergy. DOI: 10.1111/all.13843. Sven Seys, Santiago QuirceI, Ioana Agache, M.Alvaro, et al.

A perspective on the pediatric death from oral food challenge reported from the Allergy Vigilance Network. March 2019, Allergy. DOI: 10.1111/all.13791. Julia Upton, Montserrat Alvaro, Kari Nadeau.

AREAS OF EXPERTISE: 

- Chronic urticaria
- Food allergy.
- Oral immunotherapy in food allergy.
- Subcutaneous Immunotherapy: mechanisms of action, clinical applications in respiratory allergy.
- Component-resolved diagnosis in food and respiratory allergy. 

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