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Latest News

Added 19 hours ago Drug news

NICE recommends Gazyvaro (obinutuzumab) plus bendamustine chemotherapy to treat follicular lymphoma.- Roche

The National Institute for Health and Care Excellence (NICE) has issued final draft guidance recommending that use of Gazyvaro (obinutuzumab)...

Added 19 hours ago Drug news

Resubmission of Olumiant (baricitinib )to the FDA for the treatment of rheumatoid arthritis will be delayed beyond 2017- Eli Lilly + Incyte Corporation

Eli Lilly and Company and Incyte Corporation announced that a resubmission to the FDA for the New Drug Application (NDA)...

Added 19 hours ago Drug news

Faslodex (fulvestrant)approved as first line treatment for oestrogen-receptor positive, locally-advanced or metastatic breast cancer in postmenopausal women.

AstraZeneca announced that the European Commission (EC) has approved Faslodex (fulvestrant) for the treatment of oestrogen-receptor positive, locally-advanced or metastatic...

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What's on the horizon?

Marshall Pearce

Cancer immunotherapies

Posted 3 months ago

It was the winner of the 1908 Nobel prize for medicine, Paul Ehrlich, who is first credited with discussing the concept of a “magic bullet”, able to target specific cells without damaging healthy tissue. With the advent of immunotherapy, as well as antibody-drug conjugates, we are beginning to realise this vision.

Marshall Pearce

Antibody-drug conjugates (ADCs)

Posted 3 months ago

Over the past couple of decades, there have been advances in a class of drugs which for a long time was purely theoretical: antibody-drug conjugates (ADCs). The concept underlying ADCs is elegant – what if it were possible to ‘target’ particular groups of cells with a cytotoxic agent, rather than exposing every cell of the body to it?

Latest Clinical Trials

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 3 months ago

A Three-part Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of Secukinumab Treatment in Juvenile Idiopathic Arthritis Subtypes of Psoriatic and Enthesitis-related Arthritis

This is a double-blind, placebo-controlled, event-driven randomized withdrawal study to investigate the efficacy and safety of secukinumab treatment in the Juvenile Idiopathic Arthritis (JIA)...

Added 5 months ago

Post-Marketing Surveillance of Adalimumab in Korean Hidradenitis Suppurativa Subjects (HS rPMS)

The objective of this study is to evaluate the safety profile of Adalimumab for Hidradenitis Suppurativa (HS) participants in normal medical practice.

Added 5 months ago

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Latest Journal Abstracts

Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysis.

The aim of this study was to examine the associations between birth weight and lung function in a cohort of women aged 60-79 years and to combine these results with those from other...

Added 1 day ago

COPD in never smokers: results from the population-based burden of obstructive lung disease study.

Never smokers comprise a substantial proportion of patients with COPD. Their characteristics and possible risk factors in this population are not yet well defined.

Added 1 day ago

Long-term air pollution exposure and living close to busy roads are associated with COPD in women.

Lung function and exacerbations of chronic obstructive pulmonary disease (COPD) have been associated with short-term exposure to air pollution.

Added 1 day ago

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Latest Guidelines

American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia and prevention of atherosclerosis.

The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees.

Added 4 months ago

GOLD 2017 Global Strategy for the Diagnosis, Management and Prevention of COPD.

Since 2001, the Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease has been a valuable resource for healthcare professionals.

Added 2 months ago

Psoriasis overview NICE Pathways

This document contains a single pathway diagram and uses numbering to link the boxes to the associated recommendations.

Added 5 months ago

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