Medical News Feed
German Drug Data (Deutsch)
Norwegian Drug Data (Norge)
Netherlands Drug Data (Nederlands)
Swedish Drug Data (Sverige)
Want to submit or suggest content for the epgonline.org YouTube Clinical channel?
Contact us here
epgonline.org is not responsible for content on any 3rd party website
Please register to access disease diagnosis, patient management, physician tools.
By viewing the content of this web page you are both confirming your status as a healthcare professional and agreeing to our terms of use.
| Drug class description : | Opiates (opioids) / paracetamol (compound analgesics). |
| Generic Name : | Co-codamol 30/500 - codeine phosphate, paracetamol |
| Drug description : | Caplets (tablets) or capsules. |
| Presentation : | Zapain Caplets: paracetamol 500mg, codeine phosphate 30mg. Zapain Capsules: paracetamol 500mg, codeine phosphate 30mg. |
| Indications : | Relief of severe pain. |
| Adult Dosage : | Usual dose, one or two caplets or capsules every four hours as required. Maximum daily dose, 8 caplets or capsules. |
| Child Dosage : | Under 12 years, not recommended. |
| Contra Indications : | Hypersensitivity to either paracetamol or codeine, or any of the excipients of Zapain caplets or capsules. Children under 12 years of age. Moderate to severe renal or hepatic impairment. Contraindicated in patients for whom opiate medications should not be used, such as patients with acute asthma, obstructive airways disease, respiratory depression, acute alcoholism, head injuries, raised head injuries, raised intracranial pressure, after biliary surgery, patients suffering from diarrhoea of any cause, within 14 days of MAOIs. |
| Special Precautions : | Increased intracranial pressure, acute abdominal conditions, elderly, debilitated, impaired renal or heaptic function (contraindicated if severe), hypothyroidism, Addison's disease, prostatic hypertrophy, urethral stricture. Pregnancy and lactation. |
| Interactions : | Antihypertensives (including diuretics), quinine, quinidine, CNS depressants, MAOIs, tricyclic antidepressants, anticholinergics, anti-diarrhoeal agents, metoclopramide, domperidone, colestyramine, mexiletine, cimetidine. Anticoagulant effect of warfarin may be increased by prolonged regular use of paracetamol (occasional doses, no significant effect). |
| Adverse Reactions : | Most commonly, nausea, vomiting, light headedness, dizziness, sedation, shortness of breath, constipation. Also, miosis, visual disturbances, headache, bradycardia, respiratory depression, difficult micturition, urinary retention, allergic reaction. Euphoria, dysphoria, constipation, abdominal pain and pruritus may occur. |
| Manufacturer : | Goldshield |
| Drug Availability : | (POM) |
Only registered users have access to the full EPG Online Knowledge Base including drug search tools, interactive disease Knowledge Centres via the EPG Knowledge Library - with clinical and evidence based physician and research tools, MiMedia (build your own clinical media collection with everything from key opinion leader essays to mode of action videos and other multi-media content), the EPG Survey panel, health news updates and much much more.
Already Registered?
Please log-in now using our member login box.
Not a member?
Don't worry, registration is quick and FREE! We welcome all Healthcare professionals, doctors, nurses and medical students.
Register today to have full access to a wealth of drug data, educational and evidence based interactive guides across all major therapeutic areas, disease management, and clinical tools.
As a practicing Healthcare professional, you can also opt-in to join our market research panel – www.epgsurvey.com – and get paid for sharing your expert clinical opinions!
REGISTER today it only takes a minute! and it's FREE
Having problems?
Use our forgotten password facility or email us at: contact@epgonline.org