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| Drug class description : | Calcium-channel blockers (class II calcium antagonists). |
| Generic Name : | Nifedipine - angina |
| Drug description : | 10 mg, 20 mg pink sustained- release tablets marked TMR and tablet strength. |
| Presentation : | Tablets, nifedipine 10mg , 20mg . |
| Indications : | Prophylaxis of chronic stable angina. |
| Adult Dosage : | Initially 10 mg every 12 hours. Maintenance, 10 - 40 mg every 12 hours. |
| Child Dosage : | Not recommended. |
| Contra Indications : | Cardiogenic shock, unstable angina, severe aortic stenosis, within a month of MI. Pregnancy, lactation. |
| Special Precautions : | Poor cardiac reserve, heart failure, hepatic impairment, severe hypotension, diabetes, dialysis. |
| Interactions : | Antihypertensives, cimetidine, quinidine, digoxin, rifampicin, diltiazem, I.V. magnesium sulphate, grapefruit juice. |
| Adverse Reactions : | Headache, flushing, dizziness, oedema, tachycardia, hypotension, GI disturbances, lethargy, paraesthesia, skin reactions, myalgia, tremor, visual disturbances, increased urinary frequency, impotence, hypersensitivity type jaundice (rare), gingival hyperplasia, gynaecomastia. MI, ischaemic pain (discontinue). |
| Manufacturer : | Genus |
| Drug Availability : | (POM) |
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