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| Drug class description : | Cardioselective b-blockers (beta- blockers). |
| Generic Name : | Atenolol - arrhythmias/MI |
| Drug description : | Tenormin Tablets: white f- c tablets marked TENORMIN 25 and S; 100 mg orange f-c tablets marked TENORMIN and S. Tenormin LS: orange f-c scored tablets marked TENORMIN LS and S. Tenormin Injection: 10 ml ampoules. Tenormin Syrup: lemon-lime, sugar-free syrup. |
| Presentation : | Tenormin Tablets: Atenolol 25 mg , 100mg . Tenormin LS: Atenolol 50 mg . Tenormin Injection: Atenolol 0.5mg/mL. Tenormin Syrup: Atenolol 25mg/ 5mL. |
| Indications : | Cardiac arrhythmias. Early intervention in acute MI. |
| Adult Dosage : | 50 - 100 mg daily. Reduce in elderly or impaired renal function. |
| Child Dosage : | Not recommended. 2nd or 3rd degree AV block, sinus bradycardia, sick sinus syndrome, severe peripheral arterial disease, uncompensated cardiac failure, cardiogenic shock, hypotension, right ventricular failure secondary to pulmonary hypertension, significant cardiomegaly, untreated phaeochromocytoma. Metabolic acidosis. Known hypersensitivity. |
| Special Precautions : | Poor cardiac reserve should be controlled with digitalis and diuretics. First degree heart block. History of bronchospasm (cardioselective b-blockers usually have a lesser effect on airways resistance than the non- selective type but their use should be avoided in patients with wheezing or obstructive airways disease unless there are compelling clinical reasons). Diabetes. Asthenic symptoms. Cerebrovascular insufficiency. Atopy. Renal or hepatic impairment, thyrotoxicosis. General anaesthesia; consider withdrawal before elective surgery. Pregnancy, lactation. Withdraw gradually. Prinzmetal's angina, first degree heart block, less severe peripheral arterial disease, ischaemic heart disease. |
| Interactions : | Clonidine withdrawal, verapamil, diltiazem, class II calcium antagonists, class I antiarrhythmics, cardiac depressant anaesthetics, hypoglycaemics, reserpine, other antihypertensives, CNS depressants, sympathomimetics, indometacin (indomethacin), ibuprofen. |
| Adverse Reactions : | Cold extremities, sleep disturbances, bradycardia, exertional tiredness, bronchospasm, heart failure deterioration, postural hypotension, GI upset. If unexplained dry eyes or skin rash occur withdraw gradually. Precipitation of heart block, intermittent claudication, Raynaud's phenomenon, confusion, dizziness, headache, mood changes, nightmares, psychoses toxicity, purpura, thrombocytopenia, exacerbations of psoriasis, psoriaform skin reactions, visual disturbances. |
| Manufacturer : | AstraZeneca |
| Drug Availability : | (POM) |
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