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| Drug class description : | Salicylates. |
| Generic Name : | Mesalazine |
| Drug description : | Salofalk Tablets: yellow oval e-c tablets Salofalk Enema: enema. Salofalk Suppositories: suppositories. |
| Presentation : | Salofalk Tablets: Mesalazine 250mg. Salofalk Enema: Mesalazine 2g per 59mL. Salofalk Suppositories: Mesalazine 500mg. |
| Indications : | Salofalk Tablets and Salofalk Enema: Mild to moderate acute exacerbations of ulcerative colitis. Maintenance of remission. Salofalk Suppositories: Mild to moderate attacks of ulcerative colitis. |
| Adult Dosage : | Salofalk Tablets and Salofalk Enema: Acute disease, 6 daily in three divided doses; maintenance, 3 - 6 daily in divided doses. 1 rectally at night. Salofalk Suppositories: 1 - 2 suppositories two or three times daily. |
| Child Dosage : | Not recommended. |
| Contra Indications : | Hypersensitivity to salicylates, severe renal and hepatic disease, active peptic ulcer, blood clotting abnormalities. Renal impairment. Pregnancy. Advise patients to report any unexplained bleeding, bruising, sore throat or malaise; perform blood test if suspect blood dyscrasia. |
| Interactions : | Sulphonylureas, coumarin, methotrexate, probenicid, sulfinpyrazone (sulphinpyrazone), spironolactone, frusemide (furosemide), rifampicin, glucocorticoids. |
| Adverse Reactions : | Hypersensitivity reactions, increased metahaemoglobin levels, blood dyscrasias, headache, GI disturbances, hair loss. |
| Manufacturer : | Provalis |
| Drug Availability : | (POM) |
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