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| Drug class description : | Growth hormones. |
| Generic Name : | Somatropin |
| Drug description : | Powder in vials plus diluent. |
| Presentation : | Saizen: somatropin (rmc) 4 i.u. (1.33mg), 10 i.u. (3.33mg). Saizen for Easyject: somatropin (rmc) 24i.u (8mg). |
| Indications : | Saizen: Growth failure in children due to deficiency of endogenous growth hormone. Turner syndrome. Growth failure in prepubertal children due to chronic renal failure. Saizen for Easyject: Growth failure in children due to deficiency of endogenous growth hormone. Turner syndrome. |
| Adult Dosage : | Not applicable. |
| Child Dosage : | Saizen: Growth hormone deficiency, 0 .07 - 0.08 i.u./kg body-weight daily by subcutaneous or intramuscular injection or 0 .2 i.u./kg body- weight three times a week. weight three times a week. Turner syndrome, 0.09 - 0.1 i.u./ kg body-weight daily by subcutaneous injection, increasing to 0.11 - 0.14 i.u./kg body-weight daily if required. Renal failure, 0.15 i.u./kg body- weight daily by subcutaneous injection. Saizen for Easyject: Growth hormone deficiency, 0.07 - 0.10i.u./kg body weight daily by subcutaneous injection. Turner syndrome, 0.14i.u./kg body-weight daily by subcutaneous injection. |
| Contra Indications : | Epiphyseal fusion, recurrent or progressive intracranial lesion, pregnancy, lactation. |
| Special Precautions : | Intracranial lesion, intracranial hypertension, diabetes, ACTH deficiency. Monitor thyroid function. |
| Adverse Reactions : | Hypothyroidism, oedema, pain at injection site, lipoatrophy. |
| Manufacturer : | Serono |
| Drug Availability : | (POM) |
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