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| Drug class description : | Mineral supplements (minerals). |
| Generic Name : | Generic |
| Drug description : | Sterile solution for injection in ampoules or prefilled syringe. |
| Presentation : | Injection, magnesium sulphate 20% w/v, 50% w/v. |
| Indications : | Treatment of magnesium deficiency in hypomagnesaemia. To prevent further seizures associated with eclampsia. |
| Adult Dosage : | Refer to Summaries of Product Characteristics. |
| Child Dosage : | Refer to Summaries of Product Characteristics. |
| Contra Indications : | Hypersensitivity to magnesium and its salts. Hepatic encephalopathy, hepatic failure or renal failure. |
| Special Precautions : | Impaired renal function; appropriate reductions in dosage should be made. Magnesium sulphate should not be used in hepatic coma if there is risk of renal failure. Pregnancy and lactation. |
| Interactions : | Muscle relaxants, nifedipine, cardiac glycosides, neuromuscular cardiac glycosides, neuromuscular blocking drugs, CNS depressants (barbiturates, opiates, general anaesthetics). |
| Adverse Reactions : | Hypermagnesaemia. Symptoms of hypermagnesaemia may include nausea, vomiting, flushing of the skin, thirst, hypotension due to peripheral vasodilatation, drowsiness, confusion, loss of tendon reflexes due to neuromuscular blockade, muscle weakness, respiratory depression, cardiac arrhythmias, coma, and cardiac arrest. Acute ingestion of Magnesium Sulphate and similar magnesium-containing compounds may also cause gastrointestinal irritation and watery diarrhoea. |
| Manufacturer : | Aurum |
| Drug Availability : | (POM) |
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