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| Drug class description : | Antidopaminergics (anti-emetics) . |
| Generic Name : | Metoclopramide - anti-emetics |
| Drug description : | Maxolon Tablets: 5 mg, white tablets; 10 mg, white scored tablets marked MAXOLON. Maxolon Syrup: syrup. Maxolon Injection: ampoules. Maxolon SR: clear capsules marked MAXOLON SR 15, containing white sustained-release microgranules. Maxolon Paediatric Liquid: ampoules with pipette. Maxolon High Dose: ampoules. |
| Presentation : | Maxolon Tablets: Metoclopramide hydrochloride 5mg , 10mg . Maxolon Syrup: Metoclopramide hydrochloride 5mg/5 mL . Maxolon Injection: Metoclopramide hydrochloride 10mg/2 mL . Maxolon SR: Metoclopramide hydrochloride 15 mg . Maxolon Paediatric Liquid: Metoclopramide hydrochloride 1mg/ mL . Maxolon High Dose: Metoclopramide (as hydrochloride) 100mg/20 mL . |
| Indications : | Maxolon Tablets, syrup, injection and Paediatric liquid: Nausea and vomiting due to GI disorders, migraine, intolerance to failure, post-operative conditions, deep X-ray or cobalt therapy. |
| Adult Dosage : | Maxolon Tablets, Syrup and Injection: Over 20 years, 15 mg twice daily; maximum 0.5 mg/kg body-weight daily. CHILDREN and YOUNG ADULTS: Severe intractable vomiting of known cause and vomiting associated with cytotoxic drugs and radiotherapy only. Up to 10 kg body-weight, 1 mg twice daily; 10 - 14 kg, 1 mg two to three times daily; 15 - 19 kg, 2 mg two to three times daily; 20 - 29 kg, 2.5 mg three times daily; 30 - 59 kg, 5 mg three times daily; over 60 kg, as adults. Commence with lower dose, all orally, intramuscularly or intravenously; maximum 0.5 mg/kg body-weight daily. Maxolon SR: Over 20 years, 15 mg twice daily; maximum 0.5mg/kg body-weight daily. Maxolon High Dose: See data sheet |
| Child Dosage : | Maxolon Tablets, Syrup and Injection: CHILDREN and YOUNG ADULTS: Severe intractable vomiting of known cause and vomiting associated with cytotoxic drugs and radiotherapy only. Up to 10 kg body-weight, 1 mg twice daily; 10 - 14 kg, 1 mg two to three times daily; 15 - 19 kg, 2 mg two to three times daily; 20 - 29 kg, 2.5 mg three times daily; 30 - 59 kg, 5 mg three times daily; over 60 kg, as adults. Commence with lower dose, all orally, intramuscularly or intravenously; maximum 0.5mg/kg body-weight daily. Maxolon SR: Not recommended. Maxolon High Dose: See data sheet |
| Special Precautions : | Recent GI surgery, prolactin- dependent breast carcinoma, phaeochromocytoma, epilepsy, renal or hepatic impairment. Pregnancy, lactation. |
| Interactions : | Anticholinergics, phenothiazines, butyrophenones. |
| Adverse Reactions : | Extrapyramidal reactions, Raised serum prolactin. Drowsiness, diarrhoea. |
| Manufacturer : | Shire |
| Drug Availability : | (POM) |
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