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| Drug class description : | Cephalosporins. |
| Generic Name : | Cefamandole |
| Drug description : | Powder in vial. |
| Presentation : | Powder for injection, cefamandole (as nafate) 1 g. |
| Indications : | Infections of the lower respiratory tract, genito-urinary tract, bones and joints, bloodstream (septicaemia), skin and soft tissue, gall bladder and peritoneum, and pelvic inflammatory disease in women, when due to susceptible micro- organisms. |
| Adult Dosage : | 500 mg - 2 g intramuscularly or intravenously four to eight hourly; maximum 12 g daily. |
| Child Dosage : | Under 1 month, not recommended; over 1 month, 50 - 100 mg/kg daily in divided doses four to eight hourly; maximum 150 mg/kg daily. |
| Contra Indications : | Known allergy to cephalosporins. |
| Special Precautions : | Penicillin sensitivity. Impaired renal function. |
| Interactions : | Loop diuretics, aminoglycosides. Loop diuretics, aminoglycosides. |
| Adverse Reactions : | Pain at injection site, hypersensitivity reactions. GI disturbances, candidosis, eosinophilia, neutropenia, thrombocytopenia, rise in liver enzymes and blood urea. Transient hepatitis, cholestatic jaundice. Positive Coomb's test. |
| Manufacturer : | Dista |
| Drug Availability : | (POM) |
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