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| Drug class description : | Opiates (opioids) / paracetamol (compound analgesics). |
| Generic Name : | Co-Codamol 30/500 - codeine phosphate, paracetamol |
| Drug description : | Kapake Tablets: white oval scored tablets marked KAPAKE. Kapake Insts: effervescent powder in sachets. Kapake Insts 60/1000: effervescent powder in sachets. Kapake Capsules: hard capsules. |
| Presentation : | Kapake Tablets: Paracetamol 500mg, codeine phosphate 30mg. Kapake Insts: Paracetamol 500mg, codeine phosphate 30mg. Kapake Insts 60/1000: Paracetamol 1g, codeine phosphate 60mg. Kapake Capsules: Paracetamol 500mg, codeine phosphate 30mg. |
| Indications : | Severe pain. |
| Adult Dosage : | Kapake Tablets and Capsules: 1 or 2 every four hours; maximum 8 daily. Kapake Insts: 1 or 2 sachets in 150 mL of water; maximum 8 sachets daily. Kapake Insts: 60/1000: 1 sachet every four hours, each dissolved in 150 mL of water; maximum 4 sachets daily. |
| Child Dosage : | Not recommended. |
| Contra Indications : | Hypersensitivity to codeine phosphate, paracetamol or any of other ingredients. Respiratory depression, acute asthma, raised intracranial pressure or head injury, acute alcoholism, concurrent treatment with MAOIs or within two weeks of treatment. Pregnancy, lactation. |
| Special Precautions : | Elderly, prostatic hypertrophy, inflammatory or obstructive bowel disorders, Addison's disease, hepatic or renal impairment. |
| Interactions : | Alcohol, CNS depressants, MAOIs. Paracetamol absorption may be increased by metoclopramide or domperidone and decreased by colestyramine (cholestyramine). Anticoagulant effect of warfarin may be increased by prolonged regular use of paracetamol (occasional doses, no significant effect). |
| Adverse Reactions : | Tolerance, dependence, constipation, dizziness, sedation, nausea, dry mouth, blurred vision. |
| Manufacturer : | Galen |
| Drug Availability : | (POM) |
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