Medical NewsGerman Drug Data (Deutsch)
Norwegian Drug Data (Norge)
Netherlands Drug Data (Nederlands)
Swedish Drug Data (Sverige)
Want to submit or suggest content for the epgonline.org YouTube Clinical channel?
Contact us here
epgonline.org is not responsible for content on any 3rd party website
Please register to access disease diagnosis, patient management, physician tools.
By viewing the content of this web page you are both confirming your status as a healthcare professional and agreeing to our terms of use.
| Drug class description : | Indoles (prostaglandin synthetase inhibitors, non-steroidal anti- inflammatory drugs, NSAIDs). |
| Generic Name : | Indometacin (indomethacin) |
| Drug description : | Indocid Capsules: 25 mg ivory capsule marked MSD 25; 50 mg ivory capsule marked MSD 50. Indocid-R capsules: ivory opaque, transparent sustained-release capsule marked MSD 693. Indocid Suppositories: polyethylene glycol suppositories. |
| Presentation : | Indocid Capsules: Indometacin 25mg , 50mg . Indocid-R Capsules: Indometacin 75mg . Indocid Suppositories: Indometacin 100mg . |
| Indications : | Indocid Capsules and Indocid Suppositories: Rheumatoid arthritis, osteoarthritis, degenerative joint disease of the hip, ankylosing spondylitis, acute gouty arthritis, lumbago, acute peri-articular disorders, orthopaedic procedures. Dysmenorrhoea. Indocid-R: As above except acute gouty arthritis. |
| Adult Dosage : | Indocid Capsules: 50-200 mg daily in divided doses with food or an antacid. Indocid Suppositories: One at night plus one in the morning if necessary. Indocid-R: One once or twice daily. |
| Contra Indications : | Active peptic ulcer, history of gastro-intestinal lesions. Aspirin/anti-inflammatory induced allergy. Recent proctitis or rectal bleeding (suppositories). Nasal polyps with angioneurotic oedema. Pregnancy, lactation. |
| Special Precautions : | Renal or hepatic impairment; monitor on long term therapy. CNS disorders. Asthma. Predisposition to fluid retention. In chronic RA, examine eyes regularly, discontinue if changes seen. Can mask signs of infection. Coagulation defects; monitor. Diabetes. Elderly. Extracellular volume depletion, sepsis. Monitor blood and GI tract. |
| Interactions : | Salicylates, other NSAIDs, anticoagulants, lithium, corticosteroids, diuretics, antihypertensives, probenecid, aminoglycosides, methotrexate, quinolones, cyclosporin, digoxin, phenylpropanolamine, nephrotoxic drugs, mifepristone. |
| Adverse Reactions : | GI bleeding or persistent headaches (discontinue if occur). Corneal deposits, retinal disturbances (perform periodic eye tests on long-term therapy). GI intolerance, dizziness, CNS effects, blood dyscrasias, dermatological effects, cardiovascular effects, Stevens- Johnson syndrome. |
| Manufacturer : | MSD |
| Drug Availability : | (POM) |
Only registered users have access to the full EPG Online Knowledge Base including drug search tools, interactive disease Knowledge Centres via the EPG Knowledge Library - with clinical and evidence based physician and research tools, MiMedia (build your own clinical media collection with everything from key opinion leader essays to mode of action videos and other multi-media content), the EPG Survey panel, health news updates and much much more.
Already Registered?
Please log-in now using our member login box.
Not a member?
Don't worry, registration is quick and FREE! We welcome all Healthcare professionals, doctors, nurses and medical students.
Register today to have full access to a wealth of drug data, educational and evidence based interactive guides across all major therapeutic areas, disease management, and clinical tools.
As a practicing Healthcare professional, you can also opt-in to join our market research panel – www.epgsurvey.com – and get paid for sharing your expert clinical opinions!
REGISTER today it only takes a minute! and it's FREE
Having problems?
Use our forgotten password facility or email us at: contact@epgonline.org