Medical NewsGerman Drug Data (Deutsch)
Norwegian Drug Data (Norge)
Netherlands Drug Data (Nederlands)
Swedish Drug Data (Sverige)
Want to submit or suggest content for the epgonline.org YouTube Clinical channel?
Contact us here
epgonline.org is not responsible for content on any 3rd party website
![The NSCLCs account for 80% of all lung cancers and can be further subdivided into squamous-cell carcinoma, large-cell carcinoma and adenocarcinoma (which includes bronchioloalveolar-cell carcinoma [BAC]](/images/banners/nsclc.gif "The NSCLCs account for 80% of all lung cancers and can be further subdivided into squamous-cell carcinoma, large-cell carcinoma and adenocarcinoma (which includes bronchioloalveolar-cell carcinoma [BAC]")
Please register to access disease diagnosis, patient management, physician tools.
By viewing the content of this web page you are both confirming your status as a healthcare professional and agreeing to our terms of use.
| Drug class description : | Non-cardioselective b-blockers (beta-blockers) / thiazide diuretics (thiazides). |
| Generic Name : | Propranolol, bendrofluazide [bendroflumethiazide] |
| Drug description : | White capsules marked INDERETIC. |
| Presentation : | Capsules, propranolol hydrochloride 80mg, bendrofluazide 2.5mg. |
| Indications : | Hypertension. |
| Adult Dosage : | 1 twice daily. 1 twice daily. |
| Child Dosage : | Not recommended. |
| Contra Indications : | 2nd or 3rd degree AV block, sinus bradycardia, sick sinus syndrome, after prolonged fasting, severe peripheral arterial disease, uncontrolled heart failure, cardiogenic shock, hypotension, untreated phaechromocytoma. Non- cardioselective b-blockers are also generally contra-indicated in patients with obstructive airways disease or a history of bronchospasm. Anuria, severe or progressive renal failure. Known hypersensitivity to either component. Prinzmetal's angina. Metabolic acidosis. |
| Special Precautions : | Poor cardiac reserve should be controlled with digitalis and diuretics. Portal hypertension. Diabetes; metabolic acidosis. Asthenic symptoms. Cerebrovascular insufficiency. Renal or hepatic impairment, thyrotoxicosis. General anaesthesia; consider withdrawal before elective surgery. Pregnancy, lactation. Withdraw gradually. Gout, diabetes, hyperlipidaemia. Monitor electrolyte levels; thiazide diuretics can cause hypokalaemia so K +-supplements may be required. |
| Interactions : | Clonidine withdrawal, verapamil, diltiazem, class II antiarrhythmics, cardiac depressant anaesthetics, hypoglycaemics, reserpine, other antihypertensives, ergot alkaloids, cimetidine, rifampicin, theophylline, warfarin, CNS depressants, sympathomimetics, indometacin (indomethacin), ibuprofen. Lithium, NSAIDs, digitalis, allopurinol, amantadine. |
| Adverse Reactions : | Cold extremities, sleep disturbances, bradycardia, exertional tiredness, bronchospasm, heart failure deterioration, postural hypotension, GI upset, alopecia, precipitation of heart block, claudication, Raynaud's phenomenon, confusion, dizziness, mood changes, nightmares, psychoses and hallucinations, purpura, thrombocytopenia, alopecia, dry eyes, psoriasiform skin reactions, exacerbation of psoriasis, skin rashes, paraesthesia, visual disturbances, gout, photosensitivity, rash, blood dyscrasias, weakness, fatigue and/or lassitude, increase in antinuclear antibodies. |
| Manufacturer : | AstraZeneca |
| Drug Availability : | (POM) |
Only registered users have access to the full EPG Online Knowledge Base including drug search tools, interactive disease Knowledge Centres via the EPG Knowledge Library - with clinical and evidence based physician and research tools, MiMedia (build your own clinical media collection with everything from key opinion leader essays to mode of action videos and other multi-media content), the EPG Survey panel, health news updates and much much more.
Already Registered?
Please log-in now using our member login box.
Not a member?
Don't worry, registration is quick and FREE! We welcome all Healthcare professionals, doctors, nurses and medical students.
Register today to have full access to a wealth of drug data, educational and evidence based interactive guides across all major therapeutic areas, disease management, and clinical tools.
As a practicing Healthcare professional, you can also opt-in to join our market research panel – www.epgsurvey.com – and get paid for sharing your expert clinical opinions!
REGISTER today it only takes a minute! and it's FREE
Having problems?
Use our forgotten password facility or email us at: contact@epgonline.org