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| Drug class description : | Thymidine analogues (antivirals). |
| Generic Name : | Idoxuridine, dimethyl sulfoxide (dimethyl sulphoxide)dimethyl sulphoxide |
| Drug description : | Topical SolutionSolution. |
| Presentation : | A clear, colourless solution containing idoxuridine BP 5% in dimethyl sulfoxide. |
| Indications : | Cutaneous herpes simplex and herpes zoster (shingles). |
| Adult Dosage : | Administration: Herpid should be painted on the lesions and their erythematous bases four times daily for four days. Adults: Treatment should start as soon as the condition has been diagnosed, ideally within two or three days after the rash appears. Good results are less likely if treatment is not started within seven days. |
| Child Dosage : | Children under 12 years: The use of Herpid in children with malignant disease might be justified but, although not a contra-indication, its use in children under the age of 12 years is not recommended. |
| Elderly Dosage : | No specific information on the use of this product in the elderly is available. Clinical trials have included patients over 65 years and no adverse reactions specific to this age group have been reported. |
| Contra Indications : | Known hypersensitivity to either idoxuridine or dimethyl sulfoxide. Dermographia. |
| Special Precautions : | Herpid in the eye causes stinging: treat by washing out with water. The dimethyl sulfoxide in Herpid may be irritant to the skin. |
| Interactions : | Since the solvent in Herpid can increase the absorption of many substances it is important that no other topical medication be used on the same areas of skin treated with Herpid. Pregnancy and lactation Animal studies have shown idoxuridine to be teratogenic. Consequently, Herpid should not be prescribed for women who are pregnant or at risk of becoming pregnant. In a small number of cases of women who used Herpid inadvertently in early pregnancy and who were followed to term, the infant was normal in each case. |
| Adverse Reactions : | Patients often experience stinging when applying Herpid and a distinctive taste during a course of treatment; both effects are transient. Skin reactions have occasionally been reported. Over-usage of the solution may lead to maceration of the skin. |
| Manufacturer : | Astellas Pharma |
| Drug Availability : | (POM) |
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