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| Drug class description : | Not Specified |
| Generic Name : | Gonadorelin hydrochloride |
| Drug description : | Powder for injection in vials. Hospital-only. |
| Presentation : | Injection, gonadorelin hydrochloride 100 microgram. |
| Indications : | For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary. The LH response is used in testing patients with suspected gonadotropin deficiency, whether due to the hypothalamus alone or in combination with anterior pituitary failure. HRF is also indicated for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumour or surgery and/ or irradiation. |
| Adult Dosage : | 100 micrograms dose, subcutaneously or intravenously. In females for whom the phase of the menstrual cycle can be established, the test should be performed in the early follicular phase (days 1 - 7). Refer to data sheet. |
| Child Dosage : | Under one year, contraindicated. |
| Contra Indications : | Hypersensitivity to HRF or any of the components. Known or suspected pregnancy. Do not use in children under one year of age as diluent contains 2% benzyl alcohol. |
| Interactions : | The HRF test should be conducted in the absence of other drugs which directly affect the pituitary secretion of gonadotropins. |
| Adverse Reactions : | Rarely, headaches, nausea, lightheadedness, abdominal discomfort and flushing. Local swelling, occasionally with pain and pruritus at the injection site, may occur if HRF is administered subcutaneously. |
| Manufacturer : | Shire |
| Drug Availability : | (POM) |
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