Medical NewsGerman Drug Data (Deutsch)
Norwegian Drug Data (Norge)
Netherlands Drug Data (Nederlands)
Swedish Drug Data (Sverige)
Want to submit or suggest content for the epgonline.org YouTube Clinical channel?
Contact us here
epgonline.org is not responsible for content on any 3rd party website
Please register to access disease diagnosis, patient management, physician tools.
By viewing the content of this web page you are both confirming your status as a healthcare professional and agreeing to our terms of use.
| Drug class description : | Oestrogens / progestogens. |
| Generic Name : | Ethinylestradiol [ethinyloestradiol], gestodene |
| Drug description : | Sugar-coated tablets. |
| Presentation : | Tablets, ethinylestradiol 0.02mg, gestodene 0.075mg. |
| Indications : | Oral contraception and the recognised gynaecological indications for such oestrogen- progestogen combinations. |
| Adult Dosage : | 1 tablet daily for 21 days, starting on 1st day of cycle, then 7 tablet-free days. |
| Child Dosage : | Not applicable. |
| Contra Indications : | 1. CARDIOVASCULAR History of arterial or venous thrombosis, family history of venous thrombosis, other known risk factors for venous thrombosis, clotting disorders, ischaemic heart disease, angina. Transient ischaemia. Valvular heart disease, atrial fibrillation, pulmonary hypertension. Sickle cell anaemia. 2. HEPATIC History of cholestatic jaundice of pregnancy. Disorders of hepatic pregnancy. Disorders of hepatic excretion (Dubin-Johnson/Rotor syndromes). Infectious hepatitis of any type. Abnormal liver function tests. Porphyria, Liver adenoma. 3. OTHER Pemphigoid gestationis, haemolytic uraemic syndrome, chorea, otosclerosis. Hormone dependent carcinoma. Undiagnosed vaginal bleeding. Recent trophoblastic disease. Pregnancy. |
| Special Precautions : | Hypertension, Raynaud's disease, diabetes, asthma, severe depression, chronic renal disease, multiple sclerosis, renal dialysis, hyperprolactinaemia, migraine, uterine fibroids, contact lenses. Women with risk factors for venous thromboembolic disease such as body mass index >30kg/m2, varicose veins or immobility. Risk of arterial thrombosis associated with oral contraception is increased with age, smoking and obesity. There is a small increased risk of breast cancer being diagnosed in women taking oral contraceptives. Examine blood pressure, pelvic organs and breasts before, and regularly during treatment. |
| Interactions : | Rifampicin, tetracyclines, ampicillin, griseofulvin, barbiturates, phenytoin, primidone, carbamazepine, ethosuximide, chloral hydrate, dichloralphenazone, glutethimide. |
| Adverse Reactions : | Breast enlargement, bloating with fluid retention. Cramps and pains in the legs. Depression. Loss of libido. Headaches, nausea, vaginal discharge and cervical erosion. Weight gain. Breakthrough bleeding. Chloasma. REASONS FOR IMMEDIATE DISCONTINUATION OF TREATMENT: Occurrence of migraine-type headaches for the first time or frequent severe headaches. Acute visual or auditory disturbances. First signs of thrombophlebitis or thromboembolism. Rise in blood pressure. Jaundice. Pregnancy. Discontinue six weeks before major elective surgery and during they should normally be restarted two weeks after the patient is fully mobile. These recommendations need not apply to minor surgical procedures with short duration of anaesthesia and early mobilisation except minor procedures to the legs. When discontinuation is not possible, prophylactic low dose, sub- cutaneous heparin may be considered. |
| Manufacturer : | Schering Health Care |
| Drug Availability : | (POM) |
Only registered users have access to the full EPG Online Knowledge Base including drug search tools, interactive disease Knowledge Centres via the EPG Knowledge Library - with clinical and evidence based physician and research tools, MiMedia (build your own clinical media collection with everything from key opinion leader essays to mode of action videos and other multi-media content), the EPG Survey panel, health news updates and much much more.
Already Registered?
Please log-in now using our member login box.
Not a member?
Don't worry, registration is quick and FREE! We welcome all Healthcare professionals, doctors, nurses and medical students.
Register today to have full access to a wealth of drug data, educational and evidence based interactive guides across all major therapeutic areas, disease management, and clinical tools.
As a practicing Healthcare professional, you can also opt-in to join our market research panel – www.epgsurvey.com – and get paid for sharing your expert clinical opinions!
REGISTER today it only takes a minute! and it's FREE
Having problems?
Use our forgotten password facility or email us at: contact@epgonline.org