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| Drug class description : | Phenothiazines group III (antipsychotics). |
| Generic Name : | Perphenazine |
| Drug description : | 2mg tablet coded 1C; 4 mg tablet coded 2C. Both white s-c tablets. |
| Presentation : | Tablets, perphenazine 2 mg , 4mg . |
| Indications : | Psychiatric conditions, including anxiety and psychomotor agitation, chronic psychoses, schizophrenia; nausea and vomiting. |
| Adult Dosage : | 12 mg daily in divided doses. Maximum 24 mg daily. |
| Child Dosage : | Not recommended. |
| Elderly Dosage : | / - / adult dose. |
| Contra Indications : | Comatose states. Bone marrow depression. |
| Special Precautions : | Cardiovascular disease. Liver dysfunction. Parkinsonism. Pregnancy, lactation. Epilepsy, glaucoma, hypothyroidism, myaesthenia gravis, phaeochromocytoma, BPH. |
| Interactions : | CNS depressants, alcohol, analgesics, antihypertensives, antidepressants, anticonvulsants, antidiabetics, levodopa. |
| Adverse Reactions : | Acute dystonias (spasms of eye, face, neck and back muscles), akathisia (motor restlessness), parkinsonism-like syndrome (rigidity and tremor), and tardive dyskinesia, dry mouth, nasal stuffiness, difficulty in micturition, tachycardia, constipation, blurring of vision, hypotension, weight gain, hypothermia (a problem in the elderly), gynaecomastia, amenorrhoea, benign obstructive jaundice, blood dyscrasias and dermatitis, ECG irregularities, drowsiness, lethargy, fatigue, epileptiform seizures. |
| Manufacturer : | Goldshield |
| Drug Availability : | (POM) |
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