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| Drug class description : | Narcotic analgesics (opiates / opioids). |
| Generic Name : | Generic |
| Drug description : | Clear, colourless, sterile solution for injection in ampoules. |
| Presentation : | Injection, fentanyl citrate 100 microgram (2mL), 500 microgram (10mL). |
| Indications : | In low doses, it is used to provide analgesia during short surgical procedures and as a premedicant. In higher doses it is employed as an analgesic/ respiratory depressant in patients who need assisted ventilation. In combination with a neuroleptic drug, fentanyl is employed as part of the technique of neuroleptanalgesia. |
| Adult Dosage : | Refer to Summary of Product Characteristics. |
| Contra Indications : | Known hypersensitivity to fentanyl citrate; respiratory depression; obstructive airways disease, concurrent administration with monoamine oxidase inhibitors or within 2 oxidase inhibitors or within 2 weeks of their discontinuation. |
| Special Precautions : | Myasthenia gravis. Reduce dosage in the elderly, in hypothyroidism and chronic hepatic disease. Administration in labour may cause respiratory depression in the new-born infant. Opioid pre- medication may potentiate or prolong depressant effects of fentanyl citrate. Tolerance and dependence may develop with repeated use. Pregnancy and lactation. Refer to Summary of Product Characteristics. |
| Interactions : | If other narcotic or CNS- depressant drugs are used concurrently with fentanyl, the effects of the drugs may be expected to be additive. The pharmacological effects of fentanyl citrate can be reversed by naloxone. |
| Adverse Reactions : | A transient fall in blood pressure may occur following intravenous administration of Fentanyl Citrate Injection. Respiratory depression. Bradycardia, skeletal muscle rigidity (morphine-like effect). Nausea and vomiting. |
| Manufacturer : | Martindale |
| Drug Availability : | (CD) |
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