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| Drug class description : | Oxicams (non-steroidal anti- inflammatory drugs, NSAIDs). |
| Generic Name : | Piroxicam |
| Drug description : | Feldene Capsules: 10 mg maroon/ blue capsule; 20 mg maroon capsule. Both marked Pfizer and FEL 10 or FEL 20, respectively. Feldene Dispersible: 10mg white, round, scored tablet marked Pfizer and FEL 10; 20 mg white oblong tablet marked PFIZER and FEL 20. Feldene Suppositories: suppositories. Feldene Melt: off-white fast dissolving tablet. Feldene I.M. Injection: solution in ampoule. |
| Presentation : | Feldene Capsules: Piroxicam 10mg , 20mg . Feldene Dispersible: Piroxicam 10 mg , 20mg . Feldene Suppositories: Piroxicam 20 mg . Feldene Melt: Piroxicam 20 mg . Feldene I.M. Injection: Piroxicam 20mg per mL. |
| Indications : | Feldene Capsules, dispersible, suppositories and melt: Rheumatoid arthritis, osteoarthrosis, ankylosing spondylitis, acute musculo- skeletal disorders, acute gout, pain following orthopaedic, dental and other minor surgery. Feldene dispersible: juvenile chronic arthritis. Feldene IM: Initial treatment of acute conditions and acute exacerbations of chronic conditions. Pain following orthopaedic, dental and other minor surgery. |
| Adult Dosage : | Feldene Capsules, dispersible, suppositories and melt: Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, 20 mg daily as a single dose; can increase this dose by 10mg if necessary. Acute musculo-skeletal disorders, initially 40 mg daily for 2 days then 20 mg daily for 5 - 12 days. Gout, initially 40 mg as a single dose then 40 mg daily in single or divided doses for next 4 - 6 days. Dispersible tabs. may be swallowed whole or dispersed in 50 mL water; Melt tablets should be dissolved on the tongue. Feldene I.M. Injection: Same as oral dose by deep i.m. inj. into upper, outer quadrant of buttocks. Maintenance, use oral preps. |
| Child Dosage : | Feldene Capsules, dispersible, suppositories and melt: Over 6 years, JCA only; under 15 kg, 5 mg; 16 - 25 kg, 10 mg; 26 - 45kg, 15mg; over 46kg, 20mg. All daily using dispersible tabs. Feldene I.M. Injection: Not recommended. |
| Contra Indications : | Aspirin/anti-inflammatory induced allergy. Active peptic ulcer, Recent proctitis (suppositories only). |
| Special Precautions : | Patients with a history of upper GI disease. Therapy to be withdrawn if bleeding occurs. Renal or hepatic impairment, monitor on long term therapy; heart failure; elderly. Pregnancy, lactation. Phenylketonuria (Feldene Melt only). |
| Interactions : | Anticoagulants, other NSAIDs, hypoglycaemics, lithium. |
| Adverse Reactions : | GI disturbances, skin reactions, injection site reactions, oedema, CNS effects, malaise, tinnitus. |
| Manufacturer : | Pfizer |
| Drug Availability : | (POM) |
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