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| Drug class description : | Thiazide diuretics (thiazides). |
| Generic Name : | Generic |
| Drug description : | Tablets. |
| Presentation : | Tablets, bendrofluazide 2.5 mg , 5 mg , Available from APS, Ashbourne (Neo-Bendromax R ), Cox, Goldshield (Neo-NaclexR , 5 mg only), Hillcross, Norton, Regent, Sovereign (AprinoxR , generic preparation also available). |
| Indications : | Mild hypertension. Severe hypertension (in combination with other drugs). Mild to moderate other drugs). Mild to moderate heart failure where no pulmonary oedema is present. |
| Adult Dosage : | Oedema, initially 5 - 10 mg every morning or on alternate days. Maintenance, 5 - 10 mg once or twice weekly. Hypertension, 2.5 - 5 mg once daily. |
| Child Dosage : | Initially up to 400 microgram/kg daily reducing to 50 - 100 microgram/kg daily for maintenance. |
| Contra Indications : | Severe renal failure. Sulphonamide sensitivity. Lactation. |
| Special Precautions : | Hepatic or renal impairment, Addison's disease, hypercalcaemia, diabetes, gout, SLE. Monitor renal function and electrolytes. Elderly. Pregnancy. |
| Interactions : | Lithium, cardiac glycosides, corticosteroids, carbenoxolone, tubocurarine, NSAIDs, antidiabetic agents, alcohol, barbiturates, opioids, antihypertensives. |
| Adverse Reactions : | Electrolyte and metabolic disturbance. Rash, photosensitivity, blood dyscrasias, impotence, pancreatitis. |
| Drug Availability : | (POM) |
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