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| Drug class description : | Retinoids. |
| Generic Name : | Tretinoin |
| Drug description : | Cream: smooth, yellow, opaque cream. Gel: smooth, translucent yellow gel with an ethanolic odour. |
| Presentation : | Cream, tretinoin 0.025% w/w. Gel, tretinoin 0.025% w/w. |
| Indications : | Topical treatment of acne vulgaris. Acticin cream is suitable for use on dry and fair skin. Acticin gel is best suited for severe acne, for initial therapy and for oily and dark skin. |
| Adult Dosage : | Apply with the fingertips once a day, before retiring, to the skin where acne lesions appear, using enough to cover the entire affected area lightly. Application may cause a transitory feeling of warmth or slight stinging. Therapeutic results may be noticed after two to three weeks but more than six weeks therapy may be required before definite beneficial effects are seen. |
| Contra Indications : | Hypersensitivity to any ingredients of Acticin cream or gel. Personal or family history of cutaneous epitheliomas. |
| Special Precautions : | Discontinue if sensitivity reaction or chemical irritation occur. Exposure to sunlight or sun lamps should be minimised during Acticin therapy. Advise patients with sunburn not to use Acticin until fully recovered. Weather extremes, eg, wind and cold, may also cause irritation during Acticin therapy. Acticin should be kept away from the eyes, mouth, angles of the nose, mucous membranes and any open lesions or abrasions. Severe local erythema and peeling may occur at the site of application - may require less frequent use, temporary or complete discontinuation. Eczema. Pregnancy and lactation. |
| Interactions : | Possible interactions with: concomitant topical medication, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices or lime. Also, particular caution required in using preparations containing sulphur, resorcinol, or salicylic acid together with Acticin. |
| Adverse Reactions : | Skin of sensitive individuals may become excessively red, oedematous, blistered or crusted - discontinue until integrity of skin restored or adjust dose to tolerable level. Temporary hypo- or hyper-pigmentation. Heightened susceptibility to sunlight. |
| Manufacturer : | Strakan |
| Drug Availability : | (POM) |
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