Medical News Feed
German Drug Data (Deutsch)
Norwegian Drug Data (Norge)
Netherlands Drug Data (Nederlands)
Swedish Drug Data (Sverige)
Want to submit or suggest content for the epgonline.org YouTube Clinical channel?
Contact us here
epgonline.org is not responsible for content on any 3rd party website
Please register to access disease diagnosis, patient management, physician tools.
By viewing the content of this web page you are both confirming your status as a healthcare professional and agreeing to our terms of use.
| Drug class description : | Antifungals (polyene antibiotics) . |
| Generic Name : | Amphotericin B lipid complex |
| Drug description : | Sterile, pyrogen-free suspension in vial to be diluted for intravenous infusion only. 10mL vials (50mg, 50,000IU) or 20mL vials (100mg, 100,000 units). |
| Presentation : | Injection, amphotericin B lipid complex (ABLC) 5mg per mL. |
| Indications : | Treatment of severe invasive candidiasis. Second line therapy for the treatment of severe systemic fungal infections in patients who have not responded to conventional amphotericin B or other systemic antifungal agents, in those who have renal impairment or other contraindications to conventional amphotericin B, or in patients who have developed amphotericin B nephrotoxicity. Indicated as second line treatment for invasive aspergillosis, cryptococcal meningitis and disseminated cryptococcosis in HIV patients, fusariosis, coccidiomycosis, zygomycosis and coccidiomycosis, zygomycosis and blastomycosis. |
| Adult Dosage : | Refer to Summary of Product Characteristics. |
| Contra Indications : | Known hypersensitivity to any of constituents, unless in the opinion of the physician, the advantages of using Abelcet outweigh the risks of hypersensitivity. |
| Special Precautions : | Renal disease. Liver disease. Pregnancy and lactation. |
| Interactions : | Nephrotoxic drugs. Zidovudine, cyclosporin. Conventional amphotericin B as been reported to interact with antineoplastic agents, corticosteroids and corticotropin (corticotrophin, ACTH), digitalis glycosides and skeletal muscle relaxants. |
| Adverse Reactions : | Most commonly, chills, fever, nausea and vomiting. Allergic reactions including anaphylaxis, bronchospasm, dyspnoea and hypotension have also been reported. |
| Manufacturer : | The Liposome Co |
| Drug Availability : | (POM) |
Only registered users have access to the full EPG Online Knowledge Base including drug search tools, interactive disease Knowledge Centres via the EPG Knowledge Library - with clinical and evidence based physician and research tools, MiMedia (build your own clinical media collection with everything from key opinion leader essays to mode of action videos and other multi-media content), the EPG Survey panel, health news updates and much much more.
Already Registered?
Please log-in now using our member login box.
Not a member?
Don't worry, registration is quick and FREE! We welcome all Healthcare professionals, doctors, nurses and medical students.
Register today to have full access to a wealth of drug data, educational and evidence based interactive guides across all major therapeutic areas, disease management, and clinical tools.
As a practicing Healthcare professional, you can also opt-in to join our market research panel – www.epgsurvey.com – and get paid for sharing your expert clinical opinions!
REGISTER today it only takes a minute! and it's FREE
Having problems?
Use our forgotten password facility or email us at: contact@epgonline.org