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| Drug class description : | Aminoglycosides. |
| Generic Name : | Amikacin |
| Drug description : | Amikin: vials. Amikin Paediatric: vials. |
| Presentation : | Amikin: Amikacin (as sulphate) 500mg per 2mL. Amikin Paediatric: Amikacin (as sulphate) 100mg per 2mL. |
| Indications : | Short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. May also be indicated for the treatment of known or suspected staphylococcal disease. Active against a broad spectrum of Gram-negative organisms, including Pseudomonas spp., Escherichia coli, indole- positive and indole-negative Proteus spp., Klebsiella- Enterobacter-Serratia spp, Salmonella, Shigella, Minea- Herellae, Citrobacter freundii and Providencia spp. |
| Adult Dosage : | Amikin: 15 mg/kg intramuscular or intravenous injection daily in two divided doses for up to two divided doses for up to 10 days; total maximum 15 g. UTI, 7 .5 mg/kg daily in two divided doses. |
| Child Dosage : | Amikin Paediatric: Neonates, initially 10 mg/kg then 15 mg/kg daily in two divided doses; others, same as adult. |
| Contra Indications : | Pregnancy. |
| Special Precautions : | Ensure adequate hydration. Renal impairment. |
| Interactions : | Frusemide (furosemide), etacrynic acid (ethacrynic acid), anaesthetics, neuromuscular blocking drugs. |
| Adverse Reactions : | Ototoxicity, nephrotoxicity. |
| Manufacturer : | Bristol-Myers Squibb |
| Drug Availability : | (POM) |
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