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Medicine information : Amiodarone
| Drug class description : | Class III antiarrhythmics (anti- arrhythmics). |
| Generic Name : | Generic |
| Drug description : | Tablets. |
| Presentation : | Tablets, amiodarone 100mg , 200mg . Available from APS, Cox, Generics UK, Hillcross, Lagap, Norton, Sterwin. |
| Indications : | Tachyarrhythmias associated with Wolff-Parkinson-White syndrome. Wolff-Parkinson-White syndrome. Atrial flutter and fibrillation where other drugs cannot be used. All types of paroxysmal tachyarrhythmias where other drugs cannot be used. |
| Adult Dosage : | 200 mg three times daily for one week then 200 mg twice daily for one week. Maintain on minimum effective dose, usually 200 mg daily. |
| Contra Indications : | SA or AV block. Severe bradycardia. Shock. History of thyroid dysfunction. Lactation. IV: Also severe respiratory failure, circulatory collapse, severe arterial hypotension, congestive heart failure, cardiomyopathy (bolus i.v.). |
| Special Precautions : | Therapy must be initiated under hospital or specialist supervision. Monitor thyroid, pulmonary and liver function and eyes. Heart failure. Iodine sensitivity. Pregnancy. |
| Interactions : | Oral anticoagulants, digoxin, phenytoin, drugs which prolong QT interval, antiarrhythmics, erythromycin, co-trimoxazole, pentamidine, antipsychotics, lithium, TCADs, antihistamines, antimalarials, b-blockers, Ca++ antagonists, diuretics, corticosteroids, tetracosactide (tetracosactrin), amphotericin, anaesthesia, cyclosporin. |
| Adverse Reactions : | Photosensitivity, skin reactions, pulmonary toxicity, ophthalmic, hepatic, neurological, cardiac and thyroid effects. |
| Drug Availability : | (POM) |
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