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The term “isolated systolic hypertension” (ISH) describes raised systolic blood pressure with normal or low diastolic blood pressure. Some guidelines recognise two grades of isolated systolic hypertension: Lysosomal storage disorders (LSDs) are a group of progressive and often fatal genetic diseases that are caused by an inborn error of metabolism Chronic Kidney Disease (CKD) is characterised by a gradual and permanent loss of kidney function that worsens as it progresses from stages 1 to 5. One of the most common complications of CKD is anaemia. The NSCLCs account for 80% of all lung cancers and can be further subdivided into squamous-cell carcinoma, large-cell carcinoma and adenocarcinoma (which includes bronchioloalveolar-cell carcinoma [BAC]
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Medicine information : APRINOX
 
Drug class description :  Thiazide diuretics (thiazides).
Generic Name :  Bendrofluazide [bendroflumethiazide]
Drug description :  White tablets.
Presentation :  Tablets, bendrofluazide 2.5 mg , 5 mg .
Indications :  Oedema, hypertension.
Adult Dosage :  Oedema, initially 5 - 10 mg every morning or on alternate days. Maintenance, 5 - 10 mg once or twice weekly. Hypertension, 2.5 - 5 mg once daily.
Child Dosage :  Initially up to 400 microgram/kg daily reducing to 50 - 100 microgram/kg daily for maintenance.
Contra Indications :  Severe renal failure. Sulphonamide sensitivity. Lactation.
Special Precautions :  Hepatic or renal impairment, Addison's disease, hypercalcaemia, diabetes, gout, SLE. Monitor renal function and electrolytes. Elderly. Pregnancy.
Interactions :  Lithium, cardiac glycosides, corticosteroids, carbenoxolone, tubocurarine, NSAIDs, antidiabetic agents, alcohol, barbiturates, opioids, antihypertensives.
Adverse Reactions :  Electrolyte and metabolic disturbance. Rash, photosensitivity, blood dyscrasias, impotence, pancreatitis.
Manufacturer :  Sovereign
Drug Availability :  (POM)
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