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Anti-Infectives Knowledge Network

Anti-Infectives Knowledge Network

Bringing together resources from a number of major anti-infective congresses throughout 2012 and 2013, including ISICEM, EBMT, ECCMID, EHA, ESOT and TIMM; the Anti-infectives Knowledge Network shares the experience of a number of thought leaders.

Key transplantation reports and presentations from our 2013 coverage include:

Medical Videos

Lung Transplants - The Benefits and Limitations
Lung Transplants - The Benefits and Limitations
Heart Transplantation - The Reasons for Transplantation and the Success Rates
Heart Transplantation - The Reasons for Transplantation and the Success Rates
An Overview of Blood Transfusions
An Overview of Blood Transfusions
Corneal Transplant - The Diseases, Procedures and Success Rates
Corneal Transplant - The Diseases, Procedures and Success Rates

Recent Drug Updates

Clinical Guidelines

Management of cytomegalovirus infection in haemopoietic stem cell transplantation

May 2013

These evidence-based guidelines expand and adapt previous guidance (Tomblyn et al, 2009; Andrews et..

... al, 2011). While specifically focusing on allogeneic haemopoietic stem cell transplantation (HSCT), they are relevant to other areas of haematological oncology where there is an increased risk of cytomegalovirus (CMV) infection, such as haematological cancers where intense anti-T-cell therapy has been deployed (O’Brien et al, 2006).

ESCMID guideline for the diagnosis and management of Candida diseases 2012: adults with haematological malignancies and after haematopoietic stem cell transplantation (HCT)

Dec 2012

Fungal diseases still play a major role in morbidity and mortality in patients with haematological..

... malignancies, including those undergoing haematopoietic stem cell transplantation. Although Aspergillus and other filamentous fungal diseases remain a major concern, Candida infections are still a major cause of mortality. This part of the ESCMID guidelines focuses on this patient population and reviews pertaining to prophylaxis, empirical/pre-emptive and targeted therapy of Candida diseases. AntiCandida prophylaxis is only recommended for patients receiving allogeneic stem cell transplantation.

Online CME

Kidney Transplant Recipient With BK Virus Infection: Practice Points for Clinicians

Nov 2013
... latest evidence for determining best immunosuppression strategies to prevent allograft rejection and long-term health risks in SOT recipients, as well as to educate clinicians on how and when to initiate calcineurin inhibitor minimization strategies, and how to make individualized, evidence-based decisions about maintenance immunosuppression in patients with SOT.

Conditioning Approaches for Transplantation in Older Patients With Myeloid Malignancies

Nov 2013
... to review patient selection for HCT, timing of transplant, conditioning regimens, and anticipated outcomes.

Clinical Trials

Cirrhosis, Effects of TRAnsplantation and Diabetes (CETRA)

10-01-2014

This observational study is aimed at assessing insulin secretion and sensitivity by the use of a mathematical modeling from oral glucose tolerance test in subjects with liver cirrhosis undergoing orthotopic liver transplantation (OLT), before and at various time points after OLT.

Effect of Renal Transplantation on Obstructive Sleep Apnea in End Stage Renal Disease Patients (SASinTx)

19-12-2013

The purpose of this study is to investigate the effect of renal transplantation on fluid overload and its consequence on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease. It aims further to investigate the relationship between overhydration, nocturnal rostral fluid shift and..

... the severity of sleep apnea.
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